Full list of all 50 Alien: Isolation achievements worth 1,000 gamerscore. It takes around 20-25 hours to unlock all of the achievements on Xbox 360.
Completed the game without dying
Killed by the Alien 100 times
Killed 10 humans
Collected 10 Nostromo logs in the main campaign
Collected all ID tags
Completed the game without killing any humans
Completed the game on the hardest difficulty setting
Completed the game on any difficulty setting
Completed "Tomorrow, Together"
Completed "Desolation"
Completed "Transmission"
Completed "The Message"
Completed "The Descent"
Completed 10 minigames successfully
Navigated Reactor Maintenance without dying
Used the bolt gun
Completed "Consultation"
Completed "A Synthetic Solution"
Completed "Hazard Containment"
Collected 100 archive logs
Constructed one of each craftable item
Killed an android using only the maintenance jack
Used the shotgun
Escaped from android combat without taking damage
Completed "The Trap"
Caused the Alien to retreat using a molotov
Caused the Alien to retreat by using the flamethrower
Used the flamethrower
Turned off the beacon
Completed "Seegson Synthetics"
Performed 10 successful hacks
Completed "The Outbreak"
Knocked down a human or stunned an android with a non-lethal attack
Used the stun baton
Detected 30 targets with the motion tracker
Completed "The Quarantine"
Completed "The Quarantine" without being killed by the Alien
Accessed 10 different rewire points
Used the vent system 20 times
Completed "Seegson Communications"
Killed an Android
Contacted your team and escaped Comms without being attacked by an android
Used the revolver
Completed "Encounters"
Encountered the Alien in Sevastopol for the first time
Completed "Welcome to Sevastopol"
Constructed an item
Collected an ID tag
Completed "Closing the Book"
Collected an archive log