Full list of all 50 Alien: Isolation achievements worth 1,000 gamerscore. It takes around 40-50 hours to unlock all of the achievements on Xbox One.
Detected 30 targets with the motion tracker
Completed "The Quarantine"
Completed "The Quarantine" without being killed by the Alien
Completed "Seegson Communications"
Killed an Android
Contacted your team and escaped Comms without being attacked by an android
Escaped from android combat without taking damage
Used the revolver
Accessed 10 different rewire points
Used the vent system 20 times
Completed "Encounters"
Encountered the Alien in Sevastopol for the first time
Completed "Welcome to Sevastopol"
Collected an ID tag
Constructed an item
Completed "Closing the Book"
Collected an archive log
Complete the sixth mission
Complete the seventh mission
Use the stun baton
Complete the tenth mission
Complete the eleventh mission
Complete the twelfth mission
Complete the thirteenth mission
Complete the game on the hardest difficulty setting
Complete the game on any difficulty setting
Collect all ID tags
Collect 10 Nostromo logs in the main campaign
Use the flamethrower
Use the shotgun
Kill 10 humans
Cause the Alien to retreat using a molotov
Cause the Alien to retreat by using the flamethrower
Knock down a human or stun an android with a non-lethal attack
Complete the game without killing any humans
Navigate Reactor Maintenance without dying
Perform 10 successful hacks
Complete 10 minigames successfully
Construct one of each craftable item
Collect 100 archive logs
Get killed by the Alien 100 times
Complete the fourteenth mission
Complete the fifteenth mission
Complete the sixteenth mission
Complete the seventeenth mission
Complete the eighteenth mission
Use the bolt gun
Kill an android using only the maintenance jack
Turn off the beacon
Complete the game without dying