Full list of all 50 Alien: Isolation achievements worth 1,000 gamerscore. It takes around 40-50 hours to unlock all of the achievements on Xbox One.
Collected 10 Nostromo logs in the main campaign
Killed 10 humans
Completed the game on any difficulty setting
Completed the game without killing any humans
Completed "Tomorrow, Together"
Completed "Desolation"
Completed "Transmission"
Completed "The Message"
Completed "The Descent"
Completed 10 minigames successfully
Navigated Reactor Maintenance without dying
Used the bolt gun
Completed "Consultation"
Collected 100 archive logs
Completed "A Synthetic Solution"
Completed "Hazard Containment"
Constructed one of each craftable item
Used the shotgun
Completed "The Trap"
Used the flamethrower
Caused the Alien to retreat by using the flamethrower
Accessed 10 different rewire points
Turned off the beacon
Detected 30 targets with the motion tracker
Completed "Seegson Synthetics"
Performed 10 successful hacks
Completed "The Outbreak"
Used the stun baton
Knocked down a human or stunned an android with a non-lethal attack
Caused the Alien to retreat using a molotov
Completed "The Quarantine"
Completed "The Quarantine" without being killed by the Alien
Completed "Seegson Communications"
Contacted your team and escaped Comms without being attacked by an android
Used the revolver
Killed an Android
Killed an android using only the maintenance jack
Escaped from android combat without taking damage
Completed "Encounters"
Used the vent system 20 times
Encountered the Alien in Sevastopol for the first time
Collected an ID tag
Completed "Welcome to Sevastopol"
Constructed an item
Completed "Closing the Book"
Collected an archive log
Complete the game on the hardest difficulty setting
Collect all ID tags
Get killed by the Alien 100 times
Complete the game without dying