Full list of all 69 Borderlands 2 achievements worth 1,625 gamerscore. It takes around 40-50 hours to unlock all of the achievements in the base game.
The base game contains 50 achievements worth 1,000 Gamerscore, and there are 4 DLC packs containing 19 achievements worth 625 Gamerscore.
Completed the mission "My First Gun"
Completed the mission "Best Minion Ever"
Completed the mission "The Road To Sanctuary"
Completed the mission "Plan B"
Completed the mission "Hunting The Firehawk"
Reached level 5
Reached level 10
Reached level 25
Tipped Moxxi $10,000
Killed 100 enemies with the Sabre turret
Got an item from Michael Mamaril
Killed a flying enemy with a thrown Tediore weapon
Killed a Constructor without it ever building another bot
Completed the mission "Shoot This Guy in the Face"
Unlocked 10 customization items
Completed 20 side missions
Completed the mission "A Dam Fine Rescue"
Completed the mission "A Train To Catch"
Completed the mission "Rising Action"
Completed the mission "Bright Lights, Flying City"
Completed the mission "Wildlife Preservation"
Completed the mission "The Once and Future Slab"
Completed the mission "The Man Who Would Be Jack"
Completed the mission "Where Angels Fear To Tread"
Allowed a Goliath to level up four times before killing him
Discovered all named locations in Sanctuary, Opportunity, and Lynchwood
Gave Claptrap a high five
Completed level 1 of all non-level-specific challenges with a single character
Phaselocked 100 enemies
Remained in Zero's Deception mode for ten seconds straight
Gunzerked continuously for 90 seconds
Revived someone from "Fight for Your Life!" that is on your friends list
Discovered all named locations
Discovered all named locations in Eridium Blight, Arid Nexus, and Sawtooth Cauldron
Completed all side missions
Completed Round 5 of any Circle of Slaughter
Had Purple-rated gear or better equipped in every slot
Defeated Terramorphous the Invincible
Reached level 50
Defeated Jack
Discovered all named locations in Three Horns, Tundra Express, and Frostburn Canyon
I can't even capture it on my camera
Discovered all named locations in The Highlands, Thousand Cuts, and Wildlife Exploitation Preserve
Killed a Chubby
Killed Donkey Mong
Completed the mission "Data Mining"
Opened the chest at the bus stop in Fyrestone
Completed the mission "Toil And Trouble"
Redeemed 25 tokens
Purchased 5 items from the black market
Completed the mission "X Marks the Spot"
Completed all Pirate's Booty side missions
Discovered all named locations in Oasis and the surrounding Pirate's Booty zones
Completed all Campaign of Carnage side missions
Completed the mission "Long Way To The Top"
Collected 10 pictures of Moxxi in Campaign of Carnage
Completed all Hammerlock's Hunt side missions
Discovered all named locations in Hammerlock's Hunt
Completed the mission "The Fall of Nakayama"
Unsheathed 5 swords from Immortal Skeletaurs without leaving the area
Won the most challenging round in Murderlin's Temple
Wielded the Mysterious Amulet
Vanquished the Ancient Dragons of Destruction
Fed thy noble queen 3 times during one visit to her quarters
Completed thy quest by rescuing yonder queen
Showed thine worst enemy, the abomination known as "The Darkness," who is the nerdiest of them all
Introduced thyself to the White Knight
Demonstrated your skill, or lack thereof, at rolling the magical treasure orb of many sides
Slew Mister Boney Pants Guy