Full list of all 75 Borderlands 2 achievements worth 1,875 gamerscore. It takes around 60-80 hours to unlock all of the achievements in the base game.
The base game contains 69 achievements worth 1,625 Gamerscore, and there is 1 DLC pack containing 6 achievements worth 250 Gamerscore.
Completed all Hammerlock's Hunt side missions
Defeated Terramorphous the Invincible
Got an item from Michael Mamaril
Tipped Moxxi $10,000
Wielded the Mysterious Amulet
Killed Donkey Mong
Demonstrated your skill, or lack thereof, at rolling the magical treasure orb of many sides
Slew Mister Boney Pants Guy
Completed the mission "X Marks the Spot"
Had Purple-rated gear or better equipped in every slot
Completed thy quest by rescuing yonder queen
Showed thine worst enemy, the abomination known as "The Darkness," who is the nerdiest of them all
Unsheathed 5 swords from Immortal Skeletaurs without leaving the area
Introduced thyself to the White Knight
Won the most challenging round in Murderlin's Temple
Fed thy noble queen 3 times during one visit to her quarters
Vanquished the Ancient Dragons of Destruction
Completed the mission "Long Way To The Top"
Completed all Campaign of Carnage side missions
Collected 10 pictures of Moxxi in Campaign of Carnage
Discovered all named locations in Hammerlock's Hunt
Completed the mission "The Fall of Nakayama"
Gunzerked continuously for 90 seconds
Reached level 50
Defeated Jack
Completed the mission "Data Mining"
Opened the chest at the bus stop in Fyrestone
Reached level 25
Completed the mission "Toil And Trouble"
Completed the mission "Where Angels Fear To Tread"
Completed the mission "The Man Who Would Be Jack"
Completed the mission "The Once and Future Slab"
Completed the mission "Shoot This Guy in the Face"
Completed the mission "Wildlife Preservation"
Gave Claptrap a high five
Killed 100 enemies with the Sabre turret
Completed 20 side missions
Completed Round 5 of any Circle of Slaughter
Killed a Chubby
Completed level 1 of all non-level-specific challenges with a single character
Completed the mission "Bright Lights, Flying City"
I can't even capture it on my camera
Killed a Constructor without it ever building another bot
Completed the mission "Rising Action"
Completed the mission "A Train To Catch"
Purchased 5 items from the black market
Completed the mission "A Dam Fine Rescue"
Completed the mission "Hunting The Firehawk"
Reached level 10
Completed the mission "Plan B"
Completed the mission "The Road To Sanctuary"
Completed the mission "Best Minion Ever"
Revived someone from "Fight for Your Life!" that is on your friends list
Reached level 5
Completed the mission "My First Gun"
Discovered all named locations in Three Horns, Tundra Express, and Frostburn Canyon
Discovered all named locations in Sanctuary, Opportunity, and Lynchwood
Discovered all named locations in The Highlands, Thousand Cuts, and Wildlife Exploitation Preserve
Discovered all named locations in Eridium Blight, Arid Nexus, and Sawtooth Cauldron
Discovered all named locations
Redeemed 25 tokens
Unlocked 10 customization items
Allow a Goliath to level up four times before killing him
Phaselock 100 enemies
Kill a flying enemy with a thrown Tediore weapon
Remain in Zero's Deception mode for ten seconds straight
Complete all side missions
Discover all named locations in Oasis and the surrounding Pirate's Booty zones
Complete all Pirate's Booty side missions
Activate the Backburner's firewall.
Allow Tiny Tina to arm the moonshot cannon.
Defeat Haderax the Invincible.
Defeat the Dark Web.
Equip effervescent-quality gear in all slots (except class mod).
Complete the mission "Paradise Found".