Full list of all 75 Borderlands 2 achievements worth 1,875 gamerscore. It takes around 60-80 hours to unlock all of the achievements in the base game.
The base game contains 69 achievements worth 1,625 Gamerscore, and there is 1 DLC pack containing 6 achievements worth 250 Gamerscore.
Discovered all named locations
Completed level 1 of all non-level-specific challenges with a single character
Discovered all named locations in Eridium Blight, Arid Nexus, and Sawtooth Cauldron
Discovered all named locations in The Highlands, Thousand Cuts, and Wildlife Exploitation Preserve
Vanquished the Ancient Dragons of Destruction
Phaselocked 100 enemies
Completed Round 5 of any Circle of Slaughter
I can't even capture it on my camera
Discovered all named locations in Three Horns, Tundra Express, and Frostburn Canyon
Killed a Chubby
Got an item from Michael Mamaril
Completed the mission "Shoot This Guy in the Face"
Fed thy noble queen 3 times during one visit to her quarters
Demonstrated your skill, or lack thereof, at rolling the magical treasure orb of many sides
Completed thy quest by rescuing yonder queen
Defeated Terramorphous the Invincible
Unsheathed 5 swords from Immortal Skeletaurs without leaving the area
Introduced thyself to the White Knight
Reached level 50
Killed Donkey Mong
Discovered all named locations in Sanctuary, Opportunity, and Lynchwood
Killed a flying enemy with a thrown Tediore weapon
Defeated Jack
Completed 20 side missions
Slew Mister Boney Pants Guy
Opened the chest at the bus stop in Fyrestone
Completed the mission "Toil And Trouble"
Reached level 25
Completed the mission "Where Angels Fear To Tread"
Killed a Constructor without it ever building another bot
Allowed a Goliath to level up four times before killing him
Completed the mission "The Man Who Would Be Jack"
Completed the mission "The Once and Future Slab"
Completed the mission "Wildlife Preservation"
Gave Claptrap a high five
Completed the mission "Data Mining"
Revived someone from "Fight for Your Life!" that is on your friends list
Had Purple-rated gear or better equipped in every slot
Completed the mission "Bright Lights, Flying City"
Unlocked 10 customization items
Completed the mission "Rising Action"
Completed the mission "A Train To Catch"
Killed 100 enemies with the Sabre turret
Purchased 5 items from the black market
Tipped Moxxi $10,000
Completed the mission "A Dam Fine Rescue"
Redeemed 25 tokens
Completed the mission "Hunting The Firehawk"
Reached level 10
Completed the mission "Plan B"
Completed the mission "The Road To Sanctuary"
Completed the mission "Best Minion Ever"
Reached level 5
Completed the mission "My First Gun"
Gunzerk continuously for 90 seconds
Remain in Zero's Deception mode for ten seconds straight
Complete all side missions
Complete the mission "X Marks the Spot"
Discover all named locations in Oasis and the surrounding Pirate's Booty zones
Complete all Pirate's Booty side missions
Complete the mission "Long Way To The Top"
Complete all Campaign of Carnage side missions
Collect 10 pictures of Moxxi in Campaign of Carnage
Complete the mission "The Fall of Nakayama"
Complete all Hammerlock's Hunt side missions
Discover all named locations in Hammerlock's Hunt
Show thine worst enemy, the abomination known as "The Darkness," who is the nerdiest of them all
Win the most challenging round in Murderlin's Temple
Wield the Mysterious Amulet
Activate the Backburner's firewall.
Allow Tiny Tina to arm the moonshot cannon.
Defeat Haderax the Invincible.
Defeat the Dark Web.
Equip effervescent-quality gear in all slots (except class mod).
Complete the mission "Paradise Found".