Full list of all 46 Devil May Cry 4 achievements worth 1,000 gamerscore. It takes around 80-100 hours to unlock all of the achievements on Xbox 360.
Clear all Bloody Palace Mode stages with an S ranking.
Clear mission 11 in Human Mode.
Clear all missions in Devil Hunter Mode.
Clear all missions in Heaven or Hell Mode.
Clear all secret missions.
Clear stage 20 of Bloody Palace Mode.
Clear stage 30 of Bloody Palace Mode.
Complete a Stylish Rank SS (Smokin' Style!!) combo.
Complete a Stylish Rank SSS (Smokin' Sick Style!!!) combo.
Extend the Vitality Gauge to maximum capacity.
Acquire 10,000 Proud Souls.
Acquire 100,000 Proud Souls.
Acquire all of Nero's skills.
Acquire all of Dante's skills.
Defeat a total of 10,000 enemies.
Acquire 1,000,000 Proud Souls.
Clear all game modes.
Clear all Bloody Palace Mode stages.
Clear stage 90 of Bloody Palace Mode.
Clear stage 80 of Bloody Palace Mode.
Clear stage 70 of Bloody Palace Mode.
Clear stage 60 of Bloody Palace Mode.
Clear stage 50 of Bloody Palace Mode.
Clear stage 40 of Bloody Palace Mode.
Clear all missions in Dante Must Die Mode with an S ranking.
Clear all missions in Son of Sparda Mode with an S ranking.
Clear all missions in Hell and Hell Mode.
Clear the game with Super Nero (Dante).
Clear all missions in Dante Must Die Mode.
Clear mission 11 in Dante Must Die Mode.
Clear all missions in Son of Sparda Mode.
Acquire a maximum number of all items.
Clear stage 10 of Bloody Palace Mode.
Clear mission 11 in Son of Sparda Mode.
Clear all missions in Devil Hunter Mode with an S ranking.
Clear all missions in Human Mode with an S ranking.
Acquire 1,000,000 Red Orbs.
Clear mission 11 in Devil Hunter Mode.
Clear all missions in Human Mode.
Defeat a total of 1,000 enemies.
Acquire 100,000 Red Orbs.
Extend the Devil Trigger Gauge to maximum capacity.
Complete a Stylish Rank S (Smokin'!) combo.
Defeat a total of 100 enemies.
Acquire 10,000 Red Orbs.
Complete a mission with an S ranking.