Full list of all 46 Devil May Cry 4 achievements worth 1,000 gamerscore. It takes around 80-100 hours to unlock all of the achievements on Xbox 360.
Clear all missions in Dante Must Die Mode.
Clear stage 90 of Bloody Palace Mode.
Clear all Bloody Palace Mode stages.
Clear all Bloody Palace Mode stages with an S ranking.
Complete a mission with an S ranking.
Extend the Vitality Gauge to maximum capacity.
Clear all game modes.
Clear the game with Super Nero (Dante).
Clear all missions in Hell and Hell Mode.
Acquire all of Dante's skills.
Acquire all of Nero's skills.
Clear mission 11 in Dante Must Die Mode.
Acquire 1,000,000 Red Orbs.
Clear stage 80 of Bloody Palace Mode.
Clear stage 70 of Bloody Palace Mode.
Clear stage 60 of Bloody Palace Mode.
Clear stage 50 of Bloody Palace Mode.
Clear stage 40 of Bloody Palace Mode.
Clear stage 30 of Bloody Palace Mode.
Clear all missions in Heaven or Hell Mode.
Clear all missions in Son of Sparda Mode.
Clear all secret missions.
Clear mission 11 in Son of Sparda Mode.
Acquire 100,000 Proud Souls.
Extend the Devil Trigger Gauge to maximum capacity.
Clear stage 20 of Bloody Palace Mode.
Clear all missions in Human Mode.
Clear mission 11 in Human Mode.
Clear stage 10 of Bloody Palace Mode.
Clear all missions in Devil Hunter Mode.
Defeat a total of 1,000 enemies.
Acquire 10,000 Proud Souls.
Acquire 100,000 Red Orbs.
Clear mission 11 in Devil Hunter Mode.
Complete a Stylish Rank SSS (Smokin' Sick Style!!!) combo.
Defeat a total of 100 enemies.
Complete a Stylish Rank SS (Smokin' Style!!) combo.
Complete a Stylish Rank S (Smokin'!) combo.
Acquire 10,000 Red Orbs.
Clear all missions in Human Mode with an S ranking.
Clear all missions in Devil Hunter Mode with an S ranking.
This is a secret achievement. You must unlock this achievement to find out more about it.