Full list of all 84 Fallout 4 achievements worth 1,600 gamerscore. It takes around 80-100 hours to unlock all of the achievements in the base game on Xbox One.
The base game contains 50 achievements worth 1,000 Gamerscore, and there are 6 DLC packs containing 34 achievements worth 600 Gamerscore.
Complete "Nuclear Family"
Complete "Ad Victoriam"
Complete "Blind Betrayal"
Reach Maximum Happiness in a Large Settlement
Kill 5 Giant Creatures
Complete "The Nuclear Option"
Decide the Fate of the Commonwealth
Complete "Rockets' Red Glare"
Complete 50 Misc. Objectives
Collect 20 Vault-Tec Bobbleheads
Collect 10 Vault-Tec Bobbleheads
Complete "Underground Undercover"
Complete "Powering Up"
Hack 50 Terminals
Complete "Mankind-Redefined"
Reach Level 50
Complete "Institutionalized"
Complete "The Molecular Level"
Join the Railroad
Placed A Grenade Or Mine While Pickpocketing
Complete "Hunter/Hunted"
Read 20 Magazines
Kill 300 People
Get a Touchdown
Pick 50 Locks
Complete 10 Side Quests
Discover 100 Locations
Kill 300 Creatures
Complete "Dangerous Minds"
Join the Brotherhood of Steel
Complete "Reunions"
Craft 100 Items
Reach Level 25
Create 50 Weapon Mods
Recruit 5 Separate Companions
Reach Maximum Relationship Level with a Companion
Complete "Old Guns"
Get a Homerun
Play a Holotape Game
Complete "Taking Independence"
Complete "Unlikely Valentine"
Build 100 Workshop Items
Reach Level 10
Ally with 3 Settlements
Gather 1000 Resources Used For Crafting
Join the Minutemen
Complete "Sanctuary"
Reach Level 5
Complete "When Freedom Calls"
Enter The Wasteland
Complete "Restoring Order"
Complete "Headhunting"
Unlock 10 Robot Mods
Build 10 Robot Mods
Complete "Mechanical Menace"
Have 5 Tamed Creatures in a Settlement
Build One of Every Cage Type
Start a Spectated Arena Fight in a Settlement
Complete the quest "Cleansing the Land"
Collect all issues of "The Islander's Almanac" magazine
Defeat 30 Far Harbor Sea Creatures
Complete the quest "Close to Home"
Complete the quest "The Way Life Should Be"
Discover 20 Far Harbor Locations
Unlock 3 Far Harbor Workshop Locations
Complete the quest "Where You Belong"
Cook One of the New Far Harbor Recipes
Complete the quest "Far From Home"
Produce 100 objects from your builders
Assign a settler to a pillory
Display a weapon on a weapon rack, armor on an armor rack, and power armor in a power armor display.
Become Overseer
Unlock all Vault 88 build areas
Equip Vault 88 suit and Pip-Boy on a settler
Redeem 100,000 tickets at the Nuka-Cade
Establish 8 Raider Camps in the Commonwealth
Defeat 40 Nuka-World Creatures while under the effect of any Nuka-Mix flavor
Create 20 different flavors of Nuka-Cola
Complete 12 quests for any Nuka-World Raider Gangs
Collect every issue of Scav! Magazine
Complete "Power Play"
Complete "Home Sweet Home"
Complete "The Grand Tour"
Complete "Taken for a Ride"