Full list of all 84 Fallout 4 achievements worth 1,600 gamerscore. It takes around 80-100 hours to unlock all of the achievements in the base game on Xbox One.
The base game contains 50 achievements worth 1,000 Gamerscore, and there are 6 DLC packs containing 34 achievements worth 600 Gamerscore.
Reach Maximum Happiness in a Large Settlement
Complete "Ad Victoriam"
Complete "Blind Betrayal"
Complete "The Nuclear Option"
Complete "Nuclear Family"
Decide the Fate of the Commonwealth
Complete "Rockets' Red Glare"
Complete "Underground Undercover"
Complete "Powering Up"
Complete "Mankind-Redefined"
Create 50 Weapon Mods
Recruit 5 Separate Companions
Kill 5 Giant Creatures
Reach Maximum Relationship Level with a Companion
Complete 50 Misc. Objectives
Placed A Grenade Or Mine While Pickpocketing
Complete "Institutionalized"
Complete "The Molecular Level"
Reach Level 50
Collect 20 Vault-Tec Bobbleheads
Get a Touchdown
Collect 10 Vault-Tec Bobbleheads
Complete "Hunter/Hunted"
Complete "Old Guns"
Complete "Taking Independence"
Build 100 Workshop Items
Ally with 3 Settlements
Complete "Dangerous Minds"
Complete 10 Side Quests
Hack 50 Terminals
Kill 300 People
Reach Level 25
Kill 300 Creatures
Discover 100 Locations
Join the Railroad
Read 20 Magazines
Craft 100 Items
Join the Minutemen
Join the Brotherhood of Steel
Complete "Reunions"
Pick 50 Locks
Get a Homerun
Complete "Unlikely Valentine"
Gather 1000 Resources Used For Crafting
Reach Level 10
Complete "Sanctuary"
Reach Level 5
Complete "When Freedom Calls"
Enter The Wasteland
Play a Holotape Game
Complete "Restoring Order"
Complete "Headhunting"
Unlock 10 Robot Mods
Build 10 Robot Mods
Complete "Mechanical Menace"
Have 5 Tamed Creatures in a Settlement
Build One of Every Cage Type
Start a Spectated Arena Fight in a Settlement
Complete the quest "Close to Home"
Complete the quest "Cleansing the Land"
Complete the quest "The Way Life Should Be"
Unlock 3 Far Harbor Workshop Locations
Collect all issues of "The Islander's Almanac" magazine
Complete the quest "Where You Belong"
Defeat 30 Far Harbor Sea Creatures
Discover 20 Far Harbor Locations
Cook One of the New Far Harbor Recipes
Complete the quest "Far From Home"
Display a weapon on a weapon rack, armor on an armor rack, and power armor in a power armor display.
Produce 100 objects from your builders
Assign a settler to a pillory
Become Overseer
Equip Vault 88 suit and Pip-Boy on a settler
Unlock all Vault 88 build areas
Establish 8 Raider Camps in the Commonwealth
Redeem 100,000 tickets at the Nuka-Cade
Collect every issue of Scav! Magazine
Complete "Power Play"
Complete "Home Sweet Home"
Complete "The Grand Tour"
Create 20 different flavors of Nuka-Cola
Defeat 40 Nuka-World Creatures while under the effect of any Nuka-Mix flavor
Complete 12 quests for any Nuka-World Raider Gangs
Complete "Taken for a Ride"