Full list of all 84 Fallout 4 achievements worth 1,600 gamerscore. It takes around 80-100 hours to unlock all of the achievements in the base game on Xbox One.
The base game contains 50 achievements worth 1,000 Gamerscore, and there are 6 DLC packs containing 34 achievements worth 600 Gamerscore.
Complete "Nuclear Family"
Collect 20 Vault-Tec Bobbleheads
Complete "Taking Independence"
Get a Homerun
Complete "Ad Victoriam"
Complete "Blind Betrayal"
Complete "Underground Undercover"
Complete "Powering Up"
Complete "The Nuclear Option"
Decide the Fate of the Commonwealth
Complete "Mankind-Redefined"
Hack 50 Terminals
Complete "Rockets' Red Glare"
Complete "Institutionalized"
Complete "The Molecular Level"
Join the Railroad
Complete "Hunter/Hunted"
Discover 100 Locations
Reach Level 50
Complete 50 Misc. Objectives
Kill 5 Giant Creatures
Collect 10 Vault-Tec Bobbleheads
Join the Minutemen
Create 50 Weapon Mods
Recruit 5 Separate Companions
Reach Maximum Relationship Level with a Companion
Complete "Old Guns"
Craft 100 Items
Complete "Reunions"
Join the Brotherhood of Steel
Complete "Sanctuary"
Complete "Dangerous Minds"
Gather 1000 Resources Used For Crafting
Pick 50 Locks
Play a Holotape Game
Reach Level 25
Complete "Unlikely Valentine"
Complete 10 Side Quests
Ally with 3 Settlements
Get a Touchdown
Kill 300 People
Build 100 Workshop Items
Read 20 Magazines
Kill 300 Creatures
Reach Level 10
Complete "When Freedom Calls"
Reach Level 5
Enter The Wasteland
Reach Maximum Happiness in a Large Settlement
Placed A Grenade Or Mine While Pickpocketing
Complete "Mechanical Menace"
Complete "Headhunting"
Complete "Restoring Order"
Unlock 10 Robot Mods
Build 10 Robot Mods
Have 5 Tamed Creatures in a Settlement
Start a Spectated Arena Fight in a Settlement
Build One of Every Cage Type
Complete the quest "Far From Home"
Complete the quest "Where You Belong"
Complete the quest "The Way Life Should Be"
Complete the quest "Cleansing the Land"
Complete the quest "Close to Home"
Collect all issues of "The Islander's Almanac" magazine
Defeat 30 Far Harbor Sea Creatures
Discover 20 Far Harbor Locations
Unlock 3 Far Harbor Workshop Locations
Cook One of the New Far Harbor Recipes
Display a weapon on a weapon rack, armor on an armor rack, and power armor in a power armor display.
Assign a settler to a pillory
Produce 100 objects from your builders
Become Overseer
Unlock all Vault 88 build areas
Equip Vault 88 suit and Pip-Boy on a settler
Complete 12 quests for any Nuka-World Raider Gangs
Collect every issue of Scav! Magazine
Create 20 different flavors of Nuka-Cola
Establish 8 Raider Camps in the Commonwealth
Defeat 40 Nuka-World Creatures while under the effect of any Nuka-Mix flavor
Redeem 100,000 tickets at the Nuka-Cade
Complete "Taken for a Ride"
Complete "The Grand Tour"
Complete "Home Sweet Home"
Complete "Power Play"