Full list of all 84 Fallout 4 achievements worth 1,600 gamerscore. It takes around 80-100 hours to unlock all of the achievements in the base game on Xbox One.
The base game contains 50 achievements worth 1,000 Gamerscore, and there are 6 DLC packs containing 34 achievements worth 600 Gamerscore.
Reach Maximum Happiness in a Large Settlement
Complete "Nuclear Family"
Complete "Rockets' Red Glare"
Complete "Underground Undercover"
Complete "Powering Up"
Complete "Mankind-Redefined"
Complete "The Nuclear Option"
Decide the Fate of the Commonwealth
Complete "Ad Victoriam"
Complete "Blind Betrayal"
Complete "Institutionalized"
Complete "The Molecular Level"
Create 50 Weapon Mods
Complete "Hunter/Hunted"
Collect 20 Vault-Tec Bobbleheads
Kill 5 Giant Creatures
Placed A Grenade Or Mine While Pickpocketing
Reach Level 50
Complete 50 Misc. Objectives
Collect 10 Vault-Tec Bobbleheads
Complete "Old Guns"
Complete "Taking Independence"
Get a Touchdown
Complete "Dangerous Minds"
Recruit 5 Separate Companions
Craft 100 Items
Kill 300 People
Hack 50 Terminals
Join the Railroad
Reach Level 25
Complete 10 Side Quests
Build 100 Workshop Items
Complete "Reunions"
Read 20 Magazines
Kill 300 Creatures
Discover 100 Locations
Complete "Unlikely Valentine"
Pick 50 Locks
Reach Maximum Relationship Level with a Companion
Ally with 3 Settlements
Get a Homerun
Join the Brotherhood of Steel
Reach Level 10
Join the Minutemen
Complete "Sanctuary"
Gather 1000 Resources Used For Crafting
Reach Level 5
Complete "When Freedom Calls"
Enter The Wasteland
Play a Holotape Game
Complete "Restoring Order"
Build 10 Robot Mods
Complete "Headhunting"
Unlock 10 Robot Mods
Complete "Mechanical Menace"
Build One of Every Cage Type
Have 5 Tamed Creatures in a Settlement
Start a Spectated Arena Fight in a Settlement
Complete the quest "Close to Home"
Complete the quest "Cleansing the Land"
Complete the quest "The Way Life Should Be"
Defeat 30 Far Harbor Sea Creatures
Complete the quest "Where You Belong"
Collect all issues of "The Islander's Almanac" magazine
Unlock 3 Far Harbor Workshop Locations
Discover 20 Far Harbor Locations
Cook One of the New Far Harbor Recipes
Complete the quest "Far From Home"
Produce 100 objects from your builders
Display a weapon on a weapon rack, armor on an armor rack, and power armor in a power armor display.
Assign a settler to a pillory
Equip Vault 88 suit and Pip-Boy on a settler
Unlock all Vault 88 build areas
Become Overseer
Create 20 different flavors of Nuka-Cola
Redeem 100,000 tickets at the Nuka-Cade
Complete "Power Play"
Establish 8 Raider Camps in the Commonwealth
Complete "Home Sweet Home"
Collect every issue of Scav! Magazine
Complete "The Grand Tour"
Complete 12 quests for any Nuka-World Raider Gangs
Defeat 40 Nuka-World Creatures while under the effect of any Nuka-Mix flavor
Complete "Taken for a Ride"