Full list of all 84 Fallout 4 achievements worth 1,600 gamerscore. It takes around 80-100 hours to unlock all of the achievements in the base game on Xbox One.
The base game contains 50 achievements worth 1,000 Gamerscore, and there are 6 DLC packs containing 34 achievements worth 600 Gamerscore.
Kill 5 Giant Creatures
Complete 10 Side Quests
Read 20 Magazines
Complete "Ad Victoriam"
Complete "Blind Betrayal"
Create 50 Weapon Mods
Placed A Grenade Or Mine While Pickpocketing
Complete "The Nuclear Option"
Decide the Fate of the Commonwealth
Complete "Rockets' Red Glare"
Kill 300 People
Complete "Underground Undercover"
Complete "Powering Up"
Complete "Mankind-Redefined"
Complete "Institutionalized"
Complete "The Molecular Level"
Discover 100 Locations
Complete "Hunter/Hunted"
Pick 50 Locks
Reach Level 25
Complete "Old Guns"
Kill 300 Creatures
Recruit 5 Separate Companions
Ally with 3 Settlements
Complete "Taking Independence"
Join the Minutemen
Complete "Sanctuary"
Complete "Dangerous Minds"
Complete "Reunions"
Complete "Unlikely Valentine"
Gather 1000 Resources Used For Crafting
Join the Railroad
Build 100 Workshop Items
Reach Level 10
Join the Brotherhood of Steel
Play a Holotape Game
Get a Touchdown
Reach Level 5
Complete "When Freedom Calls"
Enter The Wasteland
Complete "Nuclear Family"
Reach Maximum Happiness in a Large Settlement
Complete 50 Misc. Objectives
Hack 50 Terminals
Craft 100 Items
Reach Maximum Relationship Level with a Companion
Get a Homerun
Collect 10 Vault-Tec Bobbleheads
Collect 20 Vault-Tec Bobbleheads
Reach Level 50
Complete "Restoring Order"
Complete "Headhunting"
Build 10 Robot Mods
Unlock 10 Robot Mods
Complete "Mechanical Menace"
Start a Spectated Arena Fight in a Settlement
Have 5 Tamed Creatures in a Settlement
Build One of Every Cage Type
Complete the quest "Close to Home"
Defeat 30 Far Harbor Sea Creatures
Discover 20 Far Harbor Locations
Collect all issues of "The Islander's Almanac" magazine
Complete the quest "Cleansing the Land"
Complete the quest "The Way Life Should Be"
Unlock 3 Far Harbor Workshop Locations
Cook One of the New Far Harbor Recipes
Complete the quest "Where You Belong"
Complete the quest "Far From Home"
Display a weapon on a weapon rack, armor on an armor rack, and power armor in a power armor display.
Produce 100 objects from your builders
Assign a settler to a pillory
Become Overseer
Equip Vault 88 suit and Pip-Boy on a settler
Unlock all Vault 88 build areas
Complete 12 quests for any Nuka-World Raider Gangs
Collect every issue of Scav! Magazine
Create 20 different flavors of Nuka-Cola
Establish 8 Raider Camps in the Commonwealth
Defeat 40 Nuka-World Creatures while under the effect of any Nuka-Mix flavor
Redeem 100,000 tickets at the Nuka-Cade
Complete "Taken for a Ride"
Complete "The Grand Tour"
Complete "Home Sweet Home"
Complete "Power Play"