Full list of all 84 Fallout 4 achievements worth 1,600 gamerscore. It takes around 80-100 hours to unlock all of the achievements in the base game on Xbox One.
The base game contains 50 achievements worth 1,000 Gamerscore, and there are 6 DLC packs containing 34 achievements worth 600 Gamerscore.
Complete "The Nuclear Option"
Decide the Fate of the Commonwealth
Complete "Rockets' Red Glare"
Complete "Underground Undercover"
Complete "Powering Up"
Hack 50 Terminals
Complete "Mankind-Redefined"
Complete "Institutionalized"
Complete "The Molecular Level"
Build 100 Workshop Items
Reach Level 50
Kill 5 Giant Creatures
Complete "Hunter/Hunted"
Create 50 Weapon Mods
Join the Railroad
Recruit 5 Separate Companions
Complete 10 Side Quests
Complete "Dangerous Minds"
Complete "Reunions"
Reach Maximum Relationship Level with a Companion
Complete "Unlikely Valentine"
Reach Level 25
Kill 300 People
Complete "Old Guns"
Join the Brotherhood of Steel
Discover 100 Locations
Complete "Taking Independence"
Kill 300 Creatures
Read 20 Magazines
Pick 50 Locks
Get a Touchdown
Gather 1000 Resources Used For Crafting
Ally with 3 Settlements
Complete "Sanctuary"
Reach Level 10
Join the Minutemen
Complete "When Freedom Calls"
Reach Level 5
Enter The Wasteland
Play a Holotape Game
Complete "Nuclear Family"
Complete "Blind Betrayal"
Complete "Ad Victoriam"
Reach Maximum Happiness in a Large Settlement
Complete 50 Misc. Objectives
Craft 100 Items
Placed A Grenade Or Mine While Pickpocketing
Get a Homerun
Collect 10 Vault-Tec Bobbleheads
Collect 20 Vault-Tec Bobbleheads
Build 10 Robot Mods
Complete "Restoring Order"
Complete "Headhunting"
Unlock 10 Robot Mods
Complete "Mechanical Menace"
Have 5 Tamed Creatures in a Settlement
Start a Spectated Arena Fight in a Settlement
Build One of Every Cage Type
Complete the quest "Close to Home"
Complete the quest "The Way Life Should Be"
Unlock 3 Far Harbor Workshop Locations
Discover 20 Far Harbor Locations
Complete the quest "Where You Belong"
Complete the quest "Far From Home"
Complete the quest "Cleansing the Land"
Collect all issues of "The Islander's Almanac" magazine
Defeat 30 Far Harbor Sea Creatures
Cook One of the New Far Harbor Recipes
Display a weapon on a weapon rack, armor on an armor rack, and power armor in a power armor display.
Assign a settler to a pillory
Produce 100 objects from your builders
Become Overseer
Unlock all Vault 88 build areas
Equip Vault 88 suit and Pip-Boy on a settler
Complete "The Grand Tour"
Complete "Taken for a Ride"
Complete 12 quests for any Nuka-World Raider Gangs
Collect every issue of Scav! Magazine
Create 20 different flavors of Nuka-Cola
Establish 8 Raider Camps in the Commonwealth
Defeat 40 Nuka-World Creatures while under the effect of any Nuka-Mix flavor
Redeem 100,000 tickets at the Nuka-Cade
Complete "Home Sweet Home"
Complete "Power Play"