Full list of all 84 Fallout 4 achievements worth 1,600 gamerscore. It takes around 80-100 hours to unlock all of the achievements in the base game on Xbox One.
The base game contains 50 achievements worth 1,000 Gamerscore, and there are 6 DLC packs containing 34 achievements worth 600 Gamerscore.
Complete "Nuclear Family"
Complete "Rockets' Red Glare"
Complete "Underground Undercover"
Complete "Powering Up"
Reach Maximum Happiness in a Large Settlement
Placed A Grenade Or Mine While Pickpocketing
Join the Railroad
Get a Homerun
Complete "The Nuclear Option"
Decide the Fate of the Commonwealth
Complete "Ad Victoriam"
Collect 20 Vault-Tec Bobbleheads
Complete "Mankind-Redefined"
Complete "Blind Betrayal"
Complete "Institutionalized"
Complete "The Molecular Level"
Complete "Hunter/Hunted"
Kill 5 Giant Creatures
Complete "Dangerous Minds"
Complete 50 Misc. Objectives
Complete "Reunions"
Reach Level 50
Collect 10 Vault-Tec Bobbleheads
Recruit 5 Separate Companions
Complete "Old Guns"
Complete "Taking Independence"
Complete "Unlikely Valentine"
Complete 10 Side Quests
Hack 50 Terminals
Kill 300 People
Join the Brotherhood of Steel
Discover 100 Locations
Reach Level 25
Kill 300 Creatures
Create 50 Weapon Mods
Read 20 Magazines
Pick 50 Locks
Craft 100 Items
Ally with 3 Settlements
Reach Maximum Relationship Level with a Companion
Get a Touchdown
Complete "Sanctuary"
Reach Level 10
Join the Minutemen
Gather 1000 Resources Used For Crafting
Build 100 Workshop Items
Complete "When Freedom Calls"
Reach Level 5
Enter The Wasteland
Play a Holotape Game
Complete "Restoring Order"
Complete "Headhunting"
Unlock 10 Robot Mods
Build 10 Robot Mods
Complete "Mechanical Menace"
Have 5 Tamed Creatures in a Settlement
Start a Spectated Arena Fight in a Settlement
Build One of Every Cage Type
Complete the quest "Close to Home"
Complete the quest "The Way Life Should Be"
Complete the quest "Cleansing the Land"
Collect all issues of "The Islander's Almanac" magazine
Complete the quest "Where You Belong"
Unlock 3 Far Harbor Workshop Locations
Discover 20 Far Harbor Locations
Defeat 30 Far Harbor Sea Creatures
Cook One of the New Far Harbor Recipes
Complete the quest "Far From Home"
Produce 100 objects from your builders
Display a weapon on a weapon rack, armor on an armor rack, and power armor in a power armor display.
Assign a settler to a pillory
Become Overseer
Equip Vault 88 suit and Pip-Boy on a settler
Unlock all Vault 88 build areas
Redeem 100,000 tickets at the Nuka-Cade
Complete "Power Play"
Create 20 different flavors of Nuka-Cola
Establish 8 Raider Camps in the Commonwealth
Complete "Home Sweet Home"
Complete "The Grand Tour"
Collect every issue of Scav! Magazine
Complete 12 quests for any Nuka-World Raider Gangs
Defeat 40 Nuka-World Creatures while under the effect of any Nuka-Mix flavor
Complete "Taken for a Ride"