Full list of all 40 Prototype achievements worth 1,000 gamerscore. It takes around 35-40 hours to unlock all of the achievements on Xbox 360.
You've completed Story Mode on hard difficulty.
You've achieved a Platinum Medal for all Events.
You've achieved a rating of Gold or better in all Events.
You've completed all Consume Events.
You've killed 53,596 infected.
You've acquired all nodes in the Web of Intrigue.
You've collected all Hint Collectibles scattered across New York City.
You've collected all Landmark collectibles scattered across New York City.
You've acquired all upgrades available.
You've completed Story Mode without a single death.
You've discovered the history of Elizabeth Greene.
You've discovered what happened to Alex Mercer.
You've consumed fewer than 10 Civilians during Story Mode.
You've completed the Supreme Hybrid Boss Battle.
You've discovered the truth behind Hope, Idaho.
You've completed the Mother Boss Battle.
You've completed 3 missions without causing a single Military Alert.
You've caught an object tossed by a Hydra; and have thrown it back.
You've destroyed 2,000 vehicles.
You've evaded 10 strike teams.
You've seized 50 vehicles from enemy hands.
You've consumed 50 Web Targets.
You've completed the Supreme Hunter Boss Battle.
You've shot down 50 helicopters while driving armor.
You've killed 15 characters with a single Whipfist attack.
You've brought down your wrath on 25 strike teams, erasing them from existence.
You've consumed 200 characters to regain health.
You've destroyed 25 Infected Water Towers before they hatched.
You've destroyed 20 Helicopters in a single Helicopter flight.
You're now certified to drive and fly all vehicles.
It's definitely not you. You've patsied 5 military personnel.
You've completed the Specialist Boss Fight.
You've destroyed 10 Military Bases or Infected Hives in New York City.
You've infiltrated 10 Military Bases disguised as a Commander.
You've killed 50 characters in 5 seconds.
You've completed a mission without causing a single Military Alert.
You've run over 500 characters in a single tank.
You've completed the Hunter Boss Encounter.
You've used the Upgrade Menu to acquire an Upgrade.
Web of Intrigue unlocked.