This is just to add to Xtowers solution. If you're playing in co-op, all the upgrade achievements only unlock for the data holder. In order for the second player to then get the achievements for themselves, as Xtowers says you need 73000 ES, but you also need around 20-23 mutagen canisters. (I unlocked the final upgrade when I had 23 canisters as I played a level and got all 4 canisters, which on top of the 19 I already had allowed the upgrade to unlock.) The minimum appears to be 21 canisters (Thanks to
diseased maniac for updating me.)
Once you have both the 73000 ES plus the required number of canisters follow the previous solution to get all upgrade achievements in 5 mins max! :)