For this achievement, create a Superstar and play through a career to unlock the record. 25 interceptions took me about 7 years playing as a Strong Safety (SS). Other options are to play as a Cornerback, as they can easily net you this achievement... I just happened to have a lot of luck with the SS! Keep shuffling through the player options until you get to this choice, then simply sim through the career. Takes some time, but I found that it was easy to do while working, talking online, etc. Just look over, tap A, then go back to what you are doing... Very easy!
Any questions or corrections, just PM me or leave a comment. Thanks!. :)