The 5 stats you need to get a 5 or more in are points, rebounds, steals, assists, and blocks.
You can adjust sliders to make this much easier, if you do, I suggest increasing all of yours to 100, and making the CPU's zero except for the following stats (at 100):
Take Inside Shots
Take Close Shots
Attack the Basket
Look for Post Players
This makes it so that they're way more likely to drive, making it easier to use my method to get your blocks. Also I kept Pass Accuracy at 50 for the CPU, since without it they kept turning the ball over preventing your player from getting the relevant stats.
Turn manual substitutions on and pick your team and choose a player (I chose LeBron since I'm a Miami homer and his skillset, Kevin Durant and Bron I feel are the two best choices, but with the sliders it shouldn't matter too much). Edit the line-ups and put your player at Center or Power Forward.
You now basically just want to play "linebacker" and keep moving back and forth in the paint (watch out for 3-second violations!) and start gambling, if you think they're about to shoot, jump ahead of time.
Once blocks are done, you can move the player to Point Guard. On defense, play off your man and stay close to the rim. This will get you your 5 rebounds.
Steals should be almost automatic, just mob the ball carrier on his way up. You will find it difficult to miss any reasonable shot, and the same goes for your teammates.
Sorry if this is really long winded, I wanted to be thorough. Good luck!
Note: I've been asked if the quarter length of the game matters. I had the quarter length at 5 minutes, and would not suggest going much lower as it can take some time to get all your blocks and rebounds.