I just completed this in 35 minutes or less by doing the mission "One man's trash". I got to the part with the poppers in about 30 seconds boost grinding and picking up the vat parts quickly and got usually 4% from all the poppers that come in this part. I tried to die after the Poppers were dead from regular OD using the weapon captain Ahab out of the way from Popper explosions (by the time poppers were dead they were just finished drinking and started attacking me). If everything died and he said "area clear" I just restarted mission from the pause menu. I started off doing the excalamune challenge but got only 1% every 2-3 minutes. I also had no amps equipped so things like lightning , explosions from melee killed them.