Complete The Humane Labs Raid and Series A Funding as Heist Leader or Crew.
Not so much a guide but I thought for the benefit of the people just starting out.
These two Heists are the 3rd and 4th heists out of the total of five Heists.
The 3rd being Humane and the 4th being Series A.
Here is a list of all 5 Heist and the order in which they are playable:
1- Fleeca Job
2- Prison Break
3- Humane Labs Raid
4- Series A Funding
5- Pacific Standard Job
Also its worth mentioning that you can join at the start of the finale heist and still be eligible for the achievement even though you didn't take part in any of the set-ups.
This can be handy to know if you are trying to convince a friend or a stranger to join your heist at the final stage of it.
here is a lowdown of the two heists as requested:
In order to successfully break into humane labs, there are five setup missions that need to be completed before the finale. Note that missions 01 and 02 unlock simultaneously and can be played in any order, as do missions 04 and 05.
In order to even get through the front door, you're going to need access cards. Meet up with an Agency member (who you may recongnize from another GTA title) in order to get the keycards.
The FIB will show up right after the handoff, so your crew will need to dispose of their agents and make a quick getaway.
You'll also need a heavily-armored vehicle to transport the EMP into Humane's complex. Pick it up from a mercenary outfit based out of the rock quarry in Blaine County. You only need one, but grab two just in case - there's a nice .50 caliber machine gun mounted to the roof of one.
After eliminating the guards and stealing the trucks, expect a dogged pursuit by vehicles and helicopters as you make your way back to the Sandy Shores airfield.
Once you've completed the first two setup missions you can then move onto the EMP setup. You will need to steal a Hydra jet (which has the EMP stored inside) and then bring it to Sandy Shores Airfield.
Go to the dingy and then drive to the military aircraft carrier. Enter via the south enterance and take down all guards you encounter. Make your way to the top of the carrier and steal the Hydra jet. For the players who do not get into the Hydra, there are also three other jets on the deck. Take down all pursuing jets and then make your way to Sandy Shores Airfield for a successful setup mission.
Now you must steal a Valkyria from the docks (South docks). When you reach the docks you will be met by a range of snipers, air support and normal fighters. Be prepared! Once you've made your way through the hange, killing all the enemies, take the Valkyrie and prepare for a air battle!
The Valkyrie has three weapons, two mini guns on the side for passengers and a anti-aircraft gun on the front for the co-pilot. When you take off you have to take down a number of other enemy helicopters coming towards you. Take advantage of the anti-aircraft gun to take down the helicopters fast, or jump out and use homing lauchers. Once you've destroyed all the helicopters, fly to the meeting point to recieve your payout.
Tip: You can walk around the hanger if you are careful or swim behind the enemies and climb up a ladder to get into the Valkyrie without taking down the enemies!
After you've completed getting the EMP from the Hydra, you must get it into the Humane Labs. Make sure you're in a party with each member, communication is vital!
Start off by driving to Humane Labs in the Insurgent and parking it outside. Now run up the right side so that you activate the enemy car. Let it drive through the facility unharmed. Once its clear, take out the guard on the entrance. Afterwards take the patrol guard down. Make your way up the main road, killing the lookout. Once the lookout guard is dead move up until you see 2 soldiers and 2 scientists. Either try taking the scientists first then guards or get each team member to take down a enemy each. After the enemies are dead keep moving up the main road, kill the engineer fixing the pannel and then kill the 2 scientists walking down the road. Kill the last 2 enemies at the end of the road. Now get 1 person to run back to the Insurgent and get him to bring it into the lab. Hack the control panel to get into the garage. Once the Insurgent is stored in the garage, take the Humane Lab's van out of the facility. Make sure not to attract attention of the convey driving to the lab.
Once you've left the lab, you'll recieve your paycheck and complete the final setup mission!
Humae Labs Finale
The crew will be divided in two teams of two, the ground team and the chopper team (pilot and gunner).
The ground team will Parachute into the Humane Labs and Research to infiltrate the facilitiy. They will be equipped with Night Vision googles, to use once the EMP has been activated, a Rebreather and a Scuba Suit to escape through the cooling tunnel, a Flare Gun to use as a signal to the chopper once they reach the beach. Also, a Special Carbine and Pump Action Shotgun with supressors, Grenades and Sticky Bombs.
The pilot and the gunner will hold their position and defend the ground team of any potential threat that might occur during the infiltration. They will be equipped with parachutes, night vision googles, grenades and sticky bombs
Series A Funding: Coke
In this first drug hijacking, you are tasked with stealing some cocaine from rich frat boys on their Yacht. The crew will be split into two teams, Helicopter Team and Boat Team. After each team leaves the apartment and drives to their designated spot, the fun begins.
The Boat Team will drive to the back of the yacht and infiltrate below deck. This is a tight space so use cover and go easy as there will be a sizable amount of goons. The Helicopter Team can either land on the yacht’s helipad or on the shore, where they have a good vantage point of the upper decks of the yacht. It is up to the players and the skill of the pilot. Either way you choose, fight through and clear the ship of both drug dealing frat brothers, and police by utilizing both teams. While the teams have been doing this, they should have ran across several blocks of cocaine. There are nine (9) total to collect, both above and below deck. Find them all, clear the boat and get out of their either via helicopter, boat or jet-ski.
At this point the police have been notified and will start sending choppers, take them out and lose your wanted level and head for the marker to complete the mission by handing the coke over to Trevor’s trusty side-kick, Ron.
Series A Funding: Trash Truck
The goal here is to pose as trash collectors which in-turn allows you to steal Vagos’ supply of molly pills (ecstasy) located throughout the city. Your crew will be split into two teams, Collectors who will ride on the back of the trash truck, and Operators who will be in the cabin. After leaving the apartment, get in a car and start heading to the marker to pick-up the aforementioned trash truck.
Picking it up will have some resistance, so shoot anyone that gets in your way and leave the facility with the truck on your way to the first pick up. The first one is just a tutorial, basically just have the Collectors team get off and get the trash, throw it in the back and move on. Simple right? Yeah, that’s the only one that is simple.
The next one begins the retaliation of the Vagos, when the Collectors get out the Vagos arrive so do your best to stay alive and take them out. Once they are dead put the trash in the back and move on. You will do this two more times but the alternative is just to grab the bags, throw them in the back and drive off. The crew doesn’t have to kill the Vagos, it’s up to the players. The final collection has a timer so you’re also facing the clock.
Once the final pickup is done your crew will begin to get attacked by more Vagos, this time they are angry and driving after you. Take them out as best you can while you make your escape to the meet-up point. Upon arriving at the warehouse under the bridge, Ron will greet you again for a job well done.
Series A Funding: Bikers
Care to take a guess who the bikers that Trevor wants to steal from? The Lost of course. There will be no teams for this mission so prepare your best sneaking gear for this stealth mission as you creep into The Lost’s trailer park and steal their vans full of drugs.
Everyone get in a vehicle and head for the marker as Trevor has supplied the team with some silenced weaponry for the mission. Another marker will show a nearby dinghy that you can take to The Lost’s hideout in Stab City. Once you arrive, be as quiet as possible (remember L3 is sneak) and take out any enemies you come across, keeping an eye on their cone of vision via the mini-map. If anyone gets alerted, it is mission over.
Now that The Lost members are taking a dirt nap, grab the vans at the north end of the trailer park and hightail it as fast as you can to the drop point. The MC will follow shortly after and attempt to take you out. Either shoot their tires or just keep driving. When you arrive it will be mission over.
Series A Funding: Weed
This mission once again splits the crew into two teams, Ground Team and Gun Team. After you leave the apartment, get in a car and head towards the sawmill where the Ballas are holding the weed. You are also tasked with stealing a Technical, a wonderful pickup truck with a machine gun on it.
Once you arrive the Ground Team moves in taking out any enemies they can while the Gun team snipes enemies from a distance taking out as many as they can see. The Gun team has the high ground so they will be able to take out enemies a lot easier and allow for the other team to progress. After enough of the enemies are cleared out to comfortably move around (they will continue to spawn at times so they will never be 100% gone) grab the two trucks with the Ground Team and have the Gun team rush in and grab the Technical.
As you make your escape have the Technical lead the way taking out any obstacles you come across on the road with the mary jane filled trucks running up the rear. The trucks will have to remember to watch the road as they are very top heavy and prone to flipping around a few sharp turns that are on the route to the drop off location. Once you finally arrive you will hand over the cargo and it is mission complete.
Series A Funding: Steal Meth
If your good with titles, you might be able to guess what our task is here. I will give you a hint, it involves meth. Now if you remember the story of Grand Theft Auto V, Trevor has a history with the O’Neil Brothers, and here is pretty much where it begins. Your crew is tasked to steal a tanker of ‘meth juice’ from the O’Neil farm. There are no teams for this job, so hop in a car and get on your merry way to the marker.
As you get closer to the farm you may want to scope the place out and plan your invasion. Try picking off stragglers from afar with a sniper rifle or if everyone is ready for bare, go in guns blazing, dealer’s choice. Just start picking enemies off and move up to the house and shoot through the windows taking out the enemies inside. After things die down a bit, have one player go and grab the big rig, as the rest of the team keeps the enemies at bay. Once the driver of the truck attaches it to the trailer a timer will start, have the rest of the team mount up and prepare to protect the ‘meth juice’ as the vehicle has a health bar.
Protect it all the way to the drop off point to finish the mission and prepare for the finale.
Series A Funding: Finale
Here it is, the finale, albeit a short one. Two teams, Lookout North and Lookout South, but this is timed so hop in a car and drive to the warehouse as quickly as you can. When you arrive you will be greeted with all the enemies you have just stolen drugs from, Vagos, The Lost, O’Neil crew and the Ballas. Take positions inside the warehouse at opposite ends and at make sure you in cover, they will come in droves via vehicles. If you want you can use RPGs, homing launchers and C4 to make quick work of them.
After they finally stop coming, two team members need to hop in the Technical and start protecting the other two teammates who need to drive the drugs to the drop off location. The gunner has to be alert at all times as there will be a lot coming at the crew. Watch the health on the vans and be careful as two choppers come after you.
When you arrive you will be rewarded with a cutscene and $505,000 split four ways. Now onto the final GTA Online Heist guide, and the final heist available; The Pacific Standard Job. The big one.
The 2nd Heist The Prison Break Heist has its own separate achievement.
The 1st and 5th Heists are connected in a similar way that the two Heists for this achievement are, in which you cannot get the achievement unless you have completed them both.