Basically, kill at least one person with each weapon and gadget. This will require some upgrades, and blueprints for the upgrades. You do not need any magical powers.
- Crossbow Bolt - Incendiary Bolt
- Regular Bullet - Explosive Bullet
- Grenade - Sticky Grenade
- Corvo's Blade (melee kill and stealth kill)
Mission: House of Pleasure
Item: Incandescent Paste Incendiary Bolt Blueprints
Location: Use the valve-controlled door located within the Distillery to reach the blueprint with slow time or use Blink on the up wall.
Mission:Lady Boyle's Last Party
Item: Spiked Grenade Housing Sticky Grenade Blueprints
Location: Before entering the Mansion through the side entrance (which enters into the main hall and staircase), take a left and enter a side door into a guard's room to find the blueprints on a table.
Mission: Return to the Tower
Item: Small-Scale Combustion Refinement Explosive Bullets
Location: Once you're inside Dunwall Tower, check the rooms on the second floor, and you will find this in the General's office.
Just an important note here with the Explosive Bullets !You need to get a kill with the Explosion not the bullet so aim a little right or left from the guy your trying to get the kill.
Also you can get this on the No kill/Ghost play-through .Just collected all the blueprints and go on a kill mode on the last mission, then reload your save when the achievement pops. It's the two types of pistol rounds, two types of crossbow bolts, two types of grenades, spring razor, and sword.
Good luck and have fun!:)