Start up a season from the main menu and set Ego to 0. I used the Sirloins. Try to keep your pitches in the corners of the pitching box. Also mix up your pitches. Even on 0 Ego, the CPU will knock it out of the park if you leave a pitch hanging over the middle of the plate. Also, if you throw the same pitch over and over ie (fastball) they will begin to anticipate it. This may take a few games to get the hang of the pitching.