I used a guide made by
katrina at Yo It’s Spicy blog and cut out some symptoms that I found unnecessary.
Make sure to devolve any symptoms that spontaneously evolve on you.
1. Pick Prion on casual difficulty and the following gene set up:
Catalytic Switch
Genetic Mimic
Aerocyte
Extremophile
Sympto-Stasis
2. Start in the USA
3. Evolve the following transmissions and abilities:
Drug Resistance 1 and 2
Air 1 and 2
Cold Resistance 1
Water 1 and 2
Extreme Bioaerosol
Neural Atrophy 1,2 and 3
Genetic Hardening 1 and 2
4. I recommend saving your game at this point if you would like to get the Russian Nuclear Retaliation achievement as well as the Chinese Nuclear Retaliation achievement. Evolve the ability Cold Resistance 2 for Russia or the transmissions Bird 1 and 2 for China.
5. Save your DNA points until you have 52 (there should be no more healthy people at this point). Evolve the following symptoms:
Insomnia
Paranoia
Inflammation
Seizures
Insanity
Dysentery
You may need to evolve the abilities genetic reshuffle 1, 2 and 3 throughout the rest of the guide.
6. You will see a pop up saying “icure device announced”. Wait till you see another pop up saying “icure released globally” then evolve the symptoms rash and sweating. The next pop up will be “icure a failure” and then the achievement will unlock.
There are three other achievements you can go for while going for this one.
You will see a pop up saying “Space cure mission planned”. You don’t have to do anymore evolving, simply wait for the pop ups “Space cure mission launches” and “Space cure mission failed”. The achievement will unlock after the last pop up.
You will see pop ups saying “US President taken ill”, followed by “New President of USA selected”. Wait till you see the pop up “USA threatens Russia/China” (depends if you evolved Cold Resistance 2 or Bird 1 and 2 in step 4) then evolve the symptom Paralysis. The last pop up will be “USA nukes Russia/China” and then the achievement will unlock.