In the Factory, you will discover a green exclamation point in a long room on the map aside from the room containing Slash. In this room there will be an orange computer like the one in the first room after spawning in a new room. Attack the computer to initiate dialogue from the doctor, along with his challenge. A number of intimidating enemies will spawn in the room and you will have to carefully defeat them all. Once doing so; the doctor will reward you with an item and this achievement.