To do this you'll need a fair amount of players, but not too many I was able to do it with 180 although it will vary based off what players you pull from packs and how many of them have chemistry.
Chemistry in this game is similar to 'Style' from MUT 16, to activate a chemistry in this game you'll need 5 players in your active lineup (backup players don't count) with matching chemistry. So basically you'll need 5 players in 5 different positions with one chemistry type and another 5 in 5 other positions that have a different chemistry type.
I found this easiest to do by going to the item binder and using the option to sort by chemistry at the bottom on the left and looking at which chemistry types I had the most of after that I started comparing players to make sure my current player wasn't using one of the two chemistry types that I was going for this achievement with.
It's also much easier to do this with one defense based chemistry and one offense based chemistry but still is possible using two defense/offense chemistrys.
This will probabaly mess up your lineup but you can just use the generate best lineup option once you're done to fix it.