This shouldn't pose a problem for most people. The biggest challenge is defeating the boss Titans. To defeat these you have to make good use of cover and also note where the green battery packs are located. I used whatever the latest Titan loadout I had collected at that time, but you might find a different loadout will work better for you. Be very evasive and watch for when they activate their core weapon. Its best to avoid being hit by these in particular as your health will disappear very quickly. Obviously being as accurate as you can will deplete their health quickly and the sooner you do this the better. When your health gets to one third to one half find a green battery pack as soon as possible.
Other than that it shouldn't be too much trouble as if you do die there are regular checkpoints to restart from.