Here are some perks that help greatly:
Lucky Break - Yui Kimura (Level 30+)
- Lucky Break activates any time you are injured.
While Lucky Break is active, you won't leave trails of blood for a total of 120/150/180 seconds.
Lucky Break becomes permanently deactivated for the remainder of the Trial once the total duration has elapsed.
Iron Will - Jake Park (Level 30+)
- Grunts of Pain caused by injuries are reduced by 50/75/100 %.
Calm Spirit - Jake Park (Level 35+)
- Reduces chances of alerting Crows by 80/90/100 %.
- Screams are subdued
Now, of course you have a choice, but for the last perk I'd like to use scratchmark hiders, such as:
Poised - Jane Romero (Level 35+)
- After a Generator is completed, you leave no Scratch Marks for 6/8/10 seconds
Dance With Me - Kate Denson (Level 30+)
- When performing a fast vault or leaving a Locker in a sprint, you leave no Scratch Marks for 3 seconds.
- Dance With Me has a cool-down of 60/50/40 seconds.
These perks make it easier for the killer to lose you after getting hit, and they make it easier to hide for the rest of the trial.
A good killer to be against - Doctor (Calm spirit renders his power almost useless.)
A more tedious killer to be against - Legion (Killer instinct can track you.)