The Prologue is the first mission that you play in the normal version of the game (It's excluded from the speedrun). It's typical tutorial stuff and overall has pretty weak enemies besides the first boss: Chief Watayama.
Not much to point out here besides maybe the few points below:
1.)Pick up weapons often and get used to your melee as it packs a decent punch and becomes invaluable later on if you buy the charged melee upgrade.
2.)Use your dash ability and git gud with it, there's helpful i-frames from using it and it recharges automatically 3.)Don't be afraid to use your abilities when starting out: there are recharge stations for them around the levels and often times your abilities will be invaluable to helping clear out a tough section.
Here's a more detailed guide of the level for those that would need it, the gameplay takes a little bit to get used to imo as it's very fast paced at times but definitely not impossible to master after a few hours in game!
https://guides.gamepressure.com/ruiner/guide.asp?ID=41534