The
Vine Rune will be the first rune you unlock. It is earned by going from
The Prisoner's Quarters (first area) and exiting through to the
Promenade of the Condemned.
As you work your way to the right through the
Promenade of the Condemned, you will reach an impassable area with a green blob that has a "tickle" command, next to a door. Go through this door, and you will need to defeat an Elite Undead Archer. Killing them will drop the
Vine Rune, automatically equipped as a permanent unlock.
With the
Vine Rune equipped, you will be able to interact and sprout vines to make progress through the game. It will also allow us to unlock new areas like the
Toxic Sewers accessed from
The Prisoner's Quarters.