This Achievement is located at the Victory Boulevard (North Side)
. Normally you unlock this place through the normal story progression. You will also need to unlock the weapon called 'Dieselkraftwerk'
which is located in the main story mission "Brother 2"
Fast travel / go to Victory Boulevard (North Side), head into the building from the video, go upstairs and open the door with the 'Dieselkraftwerk' weapon. Inside you will find a shrine with eh souvenir a "Dishonered Rune!".
The code for the red chest in this small room is 2161.