This achievement requires that you unlock every single skill on the tree (Which requires a total of 267 judge blood). This tree can be accessed on the pedestal to the right of the pregame lobby (Aka The Chiming Tree).
Judge blood can be obtained by defeating minibosses, bosses and by obtaining a blessing called Instant Gift (It gives you back 10% of the total judge blood that you have already spent).
You'll likely earn enough judge blood as you grind out the other achievements but if you'd want to expedite your progress I would suggest setting your health to invulnerable and the game speed to 150% in the accessibility menu to make each run as fast as you can and using all the judge blood you can between games (That way you can maximize the amount you get whenever you activate the Instant Gift blessing).
A complete list of skills can be found here:https://www.neoseeker.com/scourgebringer/The_Chiming_Tree_Sk...