Kill everyone you can. The game locks you out of loads of areas after your first murder. So you might as well take the opportunity to kill everyone you can and also get:
I killed the following poor saps:
- The cripple using oars as crutches
- The nude bowman up by the guy being roasted over the fire
- Man tied to tree (with apple on his head)
- The poor chap being roasted over the fire
- The ‘dead’ (sleeping) guy in the graveyard
- The gatekeeper with the massive key
- The ferryman (by the Basilica, not the boatman at the start)
- The two scholars inside the Basilica
- One of the cardinals inside the Basilica
Don’t try and kill the tiny lion you monster! Why would you do such a thing?