A point of interest is an area on a map that you can examine, it will be found with a hovering magnifying glass. There are many of these across every map, each sub-map, and in the airlocks between them. When you are near a Point of Interest the game will prompt you "Hold
to
EXAMINE".
These can only be found whilst playing
SOLO, as such select a map and play on "moderate" difficulty to peruse at your leisure.
Powerpix does a great guide for where to find many of these, the list is not finite though but should suffice.
https://www.powerpyx.com/rainbow-six-extraction-points-of-in...Most importantly to avoid any confusion,
a region refers to each of the four maps, so five points of interest across; "New York City", "San Francisco", "Alaska" & "Truth or Consequences" collected in any of their three sub-maps is all you will need.