Complete the first 4 missions in Act 1
1.1 Resurgence
1.2 Tunnel of Blood
1.3 Pain Train
1.4 The Crossing
These a fairly straight forward, I did have a problem with a bug on Resurgence, after lower the drawbridge stairs between the 2 buildings both my character and the bots fell off the building and couldn’t be pulled back up due to the stairs, so to be on the safe side I always jump the gaps
Nemesis Achievement
*** Spoiler - click to reveal ***On the Resurgence mission after crossing the drawbridge stairs between the 2 buildings you pass through a couple of shut doors then enter a room that has a ladder in front of you, press X at the top of the ladder to climb down instead of just running of jumping down.
Port Man Toe? Achievement
*** Spoiler - click to reveal ***This is on the Crossing Mission, as you get to the far end of the broken bridge just before you get to the ferry, on the right hand side of the bridge there is a barge, jump down from the bridge and run toward the ferry the secret collectible is in the bottom of the barge.
Brought a knife to a Gunfight
*** Spoiler - click to reveal ***Choose a character with a melee weapon, I used the spike bat but the machete would work just as well, equip the weapon and start the first mission, you should get it before you reach the end of the first story.