Posted on 18 March 14 at 11:39
Yes, ME2 is quite rough on Insanity, certainly more so than the other two games. I'd suggest using a Sentinel since they are imo by far the best class in the game because of their powers (some prefer Vanguard and that's cool too), but as for weapons/allies and so on, I can't remember too well what I used. I never had much trouble with the collector ship due to overpowered Sentinel abilities, but you should be able to manage without that. I wouldn't use Grunt personally, rather anyone with Warp, which in this game is the best thing ever. The Particle Beam is fine for a heavy weapon though, the other choices are even slower so I wouldn't bother with them except for the Cain on the last boss.
What can change the nature of a man?