Full list of all 50 Alien: Isolation achievements worth 1,000 gamerscore. It takes around 20-25 hours to unlock all of the achievements on Xbox 360.
Killed by the Alien 100 times
Killed 10 humans
Completed the game without dying
Collected all ID tags
Collected 10 Nostromo logs in the main campaign
Collected 100 archive logs
Killed an android using only the maintenance jack
Completed "The Quarantine" without being killed by the Alien
Contacted your team and escaped Comms without being attacked by an android
Completed the game without killing any humans
Completed the game on the hardest difficulty setting
Completed the game on any difficulty setting
Completed "Tomorrow, Together"
Completed "Desolation"
Completed "Transmission"
Completed "The Message"
Caused the Alien to retreat using a molotov
Completed "The Descent"
Completed 10 minigames successfully
Navigated Reactor Maintenance without dying
Used the bolt gun
Completed "Consultation"
Completed "A Synthetic Solution"
Accessed 10 different rewire points
Completed "Hazard Containment"
Used the shotgun
Constructed one of each craftable item
Completed "The Trap"
Performed 10 successful hacks
Caused the Alien to retreat by using the flamethrower
Used the flamethrower
Turned off the beacon
Killed an Android
Detected 30 targets with the motion tracker
Completed "Seegson Synthetics"
Completed "The Outbreak"
Used the stun baton
Used the vent system 20 times
Completed "The Quarantine"
Completed "Seegson Communications"
Knocked down a human or stunned an android with a non-lethal attack
Used the revolver
Escaped from android combat without taking damage
Completed "Encounters"
Encountered the Alien in Sevastopol for the first time
Completed "Welcome to Sevastopol"
Collected an ID tag
Constructed an item
Completed "Closing the Book"
Collected an archive log