Full list of all 50 Alien: Isolation achievements worth 1,000 gamerscore. It takes around 40-50 hours to unlock all of the achievements on Xbox One.
Killed by the Alien 100 times
Collected 10 Nostromo logs in the main campaign
Collected all ID tags
Killed 10 humans
Killed an android using only the maintenance jack
Completed the game on any difficulty setting
Completed the game without killing any humans
Completed "Tomorrow, Together"
Completed "Desolation"
Completed "Transmission"
Completed "The Message"
Completed "The Descent"
Completed 10 minigames successfully
Navigated Reactor Maintenance without dying
Used the bolt gun
Completed "Consultation"
Completed "A Synthetic Solution"
Collected 100 archive logs
Completed "Hazard Containment"
Used the shotgun
Completed "The Trap"
Caused the Alien to retreat using a molotov
Caused the Alien to retreat by using the flamethrower
Used the flamethrower
Used the stun baton
Turned off the beacon
Detected 30 targets with the motion tracker
Completed "Seegson Synthetics"
Constructed one of each craftable item
Performed 10 successful hacks
Completed "The Outbreak"
Escaped from android combat without taking damage
Completed "The Quarantine"
Completed "The Quarantine" without being killed by the Alien
Accessed 10 different rewire points
Used the revolver
Completed "Seegson Communications"
Contacted your team and escaped Comms without being attacked by an android
Knocked down a human or stunned an android with a non-lethal attack
Used the vent system 20 times
Killed an Android
Completed "Encounters"
Encountered the Alien in Sevastopol for the first time
Completed "Welcome to Sevastopol"
Collected an ID tag
Constructed an item
Completed "Closing the Book"
Collected an archive log
Complete the game on the hardest difficulty setting
Complete the game without dying