Full list of all 50 Alien: Isolation achievements worth 1,000 gamerscore. It takes around 40-50 hours to unlock all of the achievements on Xbox One.
Completed "The Quarantine" without being killed by the Alien
Contacted your team and escaped Comms without being attacked by an android
Completed the game on the hardest difficulty setting
Completed the game on any difficulty setting
Completed the game without killing any humans
Completed "Tomorrow, Together"
Completed "Desolation"
Completed "Transmission"
Killed 10 humans
Completed "The Message"
Completed "The Descent"
Completed 10 minigames successfully
Used the bolt gun
Completed "Consultation"
Completed "A Synthetic Solution"
Collected 100 archive logs
Completed "Hazard Containment"
Used the shotgun
Completed "The Trap"
Caused the Alien to retreat by using the flamethrower
Used the flamethrower
Turned off the beacon
Completed "Seegson Synthetics"
Caused the Alien to retreat using a molotov
Performed 10 successful hacks
Constructed one of each craftable item
Detected 30 targets with the motion tracker
Completed "The Outbreak"
Killed an android using only the maintenance jack
Used the stun baton
Completed "The Quarantine"
Completed "Seegson Communications"
Accessed 10 different rewire points
Escaped from android combat without taking damage
Knocked down a human or stunned an android with a non-lethal attack
Killed an Android
Used the vent system 20 times
Completed "Encounters"
Used the revolver
Encountered the Alien in Sevastopol for the first time
Completed "Welcome to Sevastopol"
Collected an ID tag
Constructed an item
Completed "Closing the Book"
Collected an archive log
Collect all ID tags
Collect 10 Nostromo logs in the main campaign
Navigate Reactor Maintenance without dying
Get killed by the Alien 100 times
Complete the game without dying