Full list of all 50 Alien: Isolation achievements worth 1,000 gamerscore. It takes around 40-50 hours to unlock all of the achievements on Xbox One.
Completed the game on any difficulty setting
Completed "Tomorrow, Together"
Completed "Desolation"
Completed "Transmission"
Completed "The Message"
Completed "The Descent"
Completed 10 minigames successfully
Used the bolt gun
Completed "Consultation"
Collected 100 archive logs
Completed "A Synthetic Solution"
Completed "Hazard Containment"
Detected 30 targets with the motion tracker
Used the shotgun
Constructed one of each craftable item
Completed "The Trap"
Accessed 10 different rewire points
Caused the Alien to retreat by using the flamethrower
Caused the Alien to retreat using a molotov
Used the flamethrower
Turned off the beacon
Completed "Seegson Synthetics"
Performed 10 successful hacks
Knocked down a human or stunned an android with a non-lethal attack
Killed 10 humans
Completed "The Outbreak"
Used the stun baton
Completed "The Quarantine"
Completed "Seegson Communications"
Escaped from android combat without taking damage
Killed an Android
Used the revolver
Completed "Encounters"
Encountered the Alien in Sevastopol for the first time
Used the vent system 20 times
Constructed an item
Completed "Welcome to Sevastopol"
Collected an ID tag
Completed "Closing the Book"
Collected an archive log
Complete the game on the hardest difficulty setting
Collect all ID tags
Collect 10 Nostromo logs in the main campaign
Contact your team and escape Comms without being attacked by an android
Complete the game without killing any humans
Navigate Reactor Maintenance without dying
Get killed by the Alien 100 times
Kill an android using only the maintenance jack
Complete the fifth mission without being killed by the Alien
Complete the game without dying