Full list of all 50 Alien: Isolation achievements worth 1,000 gamerscore. It takes around 40-50 hours to unlock all of the achievements on Xbox One.
Killed by the Alien 100 times
Collected 10 Nostromo logs in the main campaign
Collected all ID tags
Killed an android using only the maintenance jack
Completed the game on the hardest difficulty setting
Killed 10 humans
Completed the game without killing any humans
Completed the game without dying
Navigated Reactor Maintenance without dying
Completed "The Quarantine" without being killed by the Alien
Contacted your team and escaped Comms without being attacked by an android
Completed the game on any difficulty setting
Completed "Tomorrow, Together"
Completed "Desolation"
Completed "Transmission"
Caused the Alien to retreat using a molotov
Completed "The Message"
Completed "The Descent"
Completed 10 minigames successfully
Used the bolt gun
Completed "Consultation"
Collected 100 archive logs
Completed "A Synthetic Solution"
Completed "Hazard Containment"
Constructed one of each craftable item
Used the shotgun
Completed "The Trap"
Accessed 10 different rewire points
Caused the Alien to retreat by using the flamethrower
Used the flamethrower
Turned off the beacon
Killed an Android
Used the stun baton
Knocked down a human or stunned an android with a non-lethal attack
Detected 30 targets with the motion tracker
Performed 10 successful hacks
Completed "Seegson Synthetics"
Used the vent system 20 times
Completed "The Outbreak"
Escaped from android combat without taking damage
Completed "The Quarantine"
Completed "Seegson Communications"
Used the revolver
Completed "Encounters"
Encountered the Alien in Sevastopol for the first time
Completed "Welcome to Sevastopol"
Collected an ID tag
Constructed an item
Completed "Closing the Book"
Collected an archive log