Full list of all 69 Borderlands 2 achievements worth 1,625 gamerscore. It takes around 40-50 hours to unlock all of the achievements in the base game.
The base game contains 50 achievements worth 1,000 Gamerscore, and there are 4 DLC packs containing 19 achievements worth 625 Gamerscore.
Killed Donkey Mong
Gunzerked continuously for 90 seconds
Had Purple-rated gear or better equipped in every slot
Discovered all named locations in Eridium Blight, Arid Nexus, and Sawtooth Cauldron
Discovered all named locations in The Highlands, Thousand Cuts, and Wildlife Exploitation Preserve
I can't even capture it on my camera
Discovered all named locations in Three Horns, Tundra Express, and Frostburn Canyon
Defeated Terramorphous the Invincible
Opened the chest at the bus stop in Fyrestone
Completed Round 5 of any Circle of Slaughter
Gave Claptrap a high five
Reached level 50
Tipped Moxxi $10,000
Killed a Chubby
Killed a flying enemy with a thrown Tediore weapon
Defeated Jack
Completed the mission "Data Mining"
Completed the mission "Toil And Trouble"
Completed the mission "Where Angels Fear To Tread"
Discovered all named locations in Sanctuary, Opportunity, and Lynchwood
Completed the mission "The Man Who Would Be Jack"
Reached level 25
Completed the mission "The Once and Future Slab"
Completed the mission "Shoot This Guy in the Face"
Completed the mission "Wildlife Preservation"
Completed the mission "Bright Lights, Flying City"
Completed the mission "Rising Action"
Completed the mission "A Train To Catch"
Completed 20 side missions
Redeemed 25 tokens
Killed a Constructor without it ever building another bot
Purchased 5 items from the black market
Completed the mission "A Dam Fine Rescue"
Unlocked 10 customization items
Completed the mission "Hunting The Firehawk"
Reached level 10
Completed the mission "Plan B"
Completed the mission "The Road To Sanctuary"
Completed the mission "Best Minion Ever"
Revived someone from "Fight for Your Life!" that is on your friends list
Reached level 5
Completed the mission "My First Gun"
Complete level 1 of all non-level-specific challenges with a single character
Allow a Goliath to level up four times before killing him
Discover all named locations
Kill 100 enemies with the Sabre turret
Phaselock 100 enemies
Get an item from Michael Mamaril
Remain in Zero's Deception mode for ten seconds straight
Complete all side missions
Discovered all named locations in Oasis and the surrounding Pirate's Booty zones
Completed the mission "X Marks the Spot"
Complete all Pirate's Booty side missions
Completed all Campaign of Carnage side missions
Completed the mission "Long Way To The Top"
Collect 10 pictures of Moxxi in Campaign of Carnage
Completed all Hammerlock's Hunt side missions
Completed the mission "The Fall of Nakayama"
Discover all named locations in Hammerlock's Hunt
Demonstrated your skill, or lack thereof, at rolling the magical treasure orb of many sides
Vanquished the Ancient Dragons of Destruction
Wielded the Mysterious Amulet
Fed thy noble queen 3 times during one visit to her quarters
Won the most challenging round in Murderlin's Temple
Completed thy quest by rescuing yonder queen
Showed thine worst enemy, the abomination known as "The Darkness," who is the nerdiest of them all
Unsheathed 5 swords from Immortal Skeletaurs without leaving the area
Introduced thyself to the White Knight
Slew Mister Boney Pants Guy