Full list of all 46 Devil May Cry 4 achievements worth 1,000 gamerscore. It takes around 80-100 hours to unlock all of the achievements on Xbox 360.
Clear mission 11 in Human Mode.
Clear all missions in Human Mode.
Clear mission 11 in Devil Hunter Mode.
Clear all missions in Devil Hunter Mode.
Clear mission 11 in Son of Sparda Mode.
Clear all missions in Son of Sparda Mode.
Clear mission 11 in Dante Must Die Mode.
Clear all missions in Dante Must Die Mode.
Clear all missions in Heaven or Hell Mode.
Clear all missions in Hell and Hell Mode.
Clear all missions in Human Mode with an S ranking.
Clear all missions in Devil Hunter Mode with an S ranking.
Clear all missions in Son of Sparda Mode with an S ranking.
Clear all missions in Dante Must Die Mode with an S ranking.
Clear all game modes.
Clear all secret missions.
Clear stage 10 of Bloody Palace Mode.
Clear stage 20 of Bloody Palace Mode.
Clear stage 30 of Bloody Palace Mode.
Clear stage 40 of Bloody Palace Mode.
Clear stage 50 of Bloody Palace Mode.
Clear stage 60 of Bloody Palace Mode.
Clear stage 70 of Bloody Palace Mode.
Clear stage 80 of Bloody Palace Mode.
Clear stage 90 of Bloody Palace Mode.
Clear all Bloody Palace Mode stages.
Clear all Bloody Palace Mode stages with an S ranking.
Clear the game with Super Nero (Dante).
Complete a Stylish Rank S (Smokin'!) combo.
Complete a Stylish Rank SS (Smokin' Style!!) combo.
Complete a Stylish Rank SSS (Smokin' Sick Style!!!) combo.
Complete a mission with an S ranking.
Extend the Vitality Gauge to maximum capacity.
Extend the Devil Trigger Gauge to maximum capacity.
Acquire 10,000 Red Orbs.
Acquire 100,000 Red Orbs.
Acquire 1,000,000 Red Orbs.
Acquire 10,000 Proud Souls.
Acquire 100,000 Proud Souls.
Acquire 1,000,000 Proud Souls.
Defeat a total of 100 enemies.
Defeat a total of 1,000 enemies.
Defeat a total of 10,000 enemies.
Acquire a maximum number of all items.
Acquire all of Nero's skills.
Acquire all of Dante's skills.