Full list of all 55 Devil May Cry 5 achievements worth 1,270 gamerscore. It takes around 60-80 hours to unlock all of the achievements in the base game.
The base game contains 48 achievements worth 1,000 Gamerscore, and there are 2 DLC packs containing 7 achievements worth 270 Gamerscore.
Clear all missions with S rank on all difficulties except Heaven or Hell.
Use more than 500,000 Red Orbs total with Dr. Faust.
Clear Mission 11 without equipping a weapon set for Dante (any difficulty except Heaven or Hell).
Beat Mission 07 without any starting Devil Breakers equipped (any difficulty except Heaven or Hell).
Collected Red Orbs from an unexpected spot in Mission 02.
Complete the game on Human mode.
Clear Mission 05 without V's demons getting stalemated (any difficulty except Heaven or Hell).
Complete the game on Hell and Hell mode.
Complete the game on Heaven or Hell mode.
Clear all missions with S rank.
Acquire all of V's skills.
Acquire all of Nero's skills.
Collect more than 100 Devil Breakers during missions.
Acquire all of Dante's skills.
Wield overwhelming power to exact an unexpected conclusion.
Complete the game on Dante Must Die mode.
Proceed with caution and avoid unneeded damage in Mission 15.
Clear Mission 13 with Nero, V, and Dante.
Upgrade your Devil Trigger Gauge to max.
Destroy a certain wall in Mission 09.
Upgrade your vitality gauge to max.
Clear Mission 07 with both Nero and V.
Complete the game on Son of Sparda mode.
Clear all secret missions.
Defeat 1,000 enemies total.
Collect more than 1,000,000 Red Orbs total.
Accept a new job from Morrison after the Red Grave incident.
Clear Missions 19 and 20 without using continues (any difficulty except Heaven or Hell).
Complete the game on Devil Hunter mode.
Defeat 5 enemies in 1 second.
Clear Mission 18.
Clear Mission 17.
Go on the offensive without relying on brute force in the Mission 16 boss battle.
Clear Mission 14.
Clear Mission 12.
Use proper timing to get a leg up in a close-quarters battle against the boss in Mission 11.
Rack up a total of 60 minutes in the air by jumping or other means.
Clear Mission 10.
Perform a Stylish Rank SSS combo.
Clear Mission 08.
Clear Mission 06.
Fend off a menace from above in Mission 05.
Destroy a certain wall in Mission 04.
Perform a Stylish Rank SS combo.
Clear Mission 03.
Perform a Stylish Rank S combo.
Defeat all enemies in Mission 01.
Clear the Prologue Mission.
Clear the Bloody Palace with V.
Clear the Bloody Palace with Nero.
Clear the Bloody Palace with Dante.
Clear all missions as Vergil.
Acquire all of Vergil's skills.
Clear Mission 19 as Vergil without using any weapons other than Yamato. (Heaven or Hell excluded)
Clear the Bloody Palace as Vergil.