Full list of all 55 Devil May Cry 5 achievements worth 1,270 gamerscore. It takes around 60-80 hours to unlock all of the achievements in the base game.
The base game contains 48 achievements worth 1,000 Gamerscore, and there are 2 DLC packs containing 7 achievements worth 270 Gamerscore.
Clear Mission 07 with both Nero and V.
Defeat 1,000 enemies total.
Collect more than 1,000,000 Red Orbs total.
Wield overwhelming power to exact an unexpected conclusion.
Defeat all enemies in Mission 01.
Perform a Stylish Rank SSS combo.
Destroy a certain wall in Mission 09.
Accept a new job from Morrison after the Red Grave incident.
Complete the game on Devil Hunter mode.
Clear Mission 18.
Clear Mission 17.
Go on the offensive without relying on brute force in the Mission 16 boss battle.
Rack up a total of 60 minutes in the air by jumping or other means.
Proceed with caution and avoid unneeded damage in Mission 15.
Clear Mission 14.
Clear Mission 12.
Use proper timing to get a leg up in a close-quarters battle against the boss in Mission 11.
Clear Mission 10.
Clear Mission 08.
Clear Mission 06.
Perform a Stylish Rank SS combo.
Destroy a certain wall in Mission 04.
Clear Mission 03.
Perform a Stylish Rank S combo.
Clear the Prologue Mission.
Complete the game on Human mode.
Complete the game on Son of Sparda mode.
Complete the game on Dante Must Die mode.
Complete the game on Heaven or Hell mode.
Complete the game on Hell and Hell mode.
Collected Red Orbs from an unexpected spot in Mission 02.
Fend off a menace from above in Mission 05.
Clear Mission 13 with Nero, V, and Dante.
Clear Missions 19 and 20 without using continues (any difficulty except Heaven or Hell).
Clear all secret missions.
Defeat 5 enemies in 1 second.
Clear all missions with S rank.
Clear all missions with S rank on all difficulties except Heaven or Hell.
Acquire all of Nero's skills.
Acquire all of Dante's skills.
Acquire all of V's skills.
Upgrade your vitality gauge to max.
Upgrade your Devil Trigger Gauge to max.
Collect more than 100 Devil Breakers during missions.
Use more than 500,000 Red Orbs total with Dr. Faust.
Clear Mission 11 without equipping a weapon set for Dante (any difficulty except Heaven or Hell).
Beat Mission 07 without any starting Devil Breakers equipped (any difficulty except Heaven or Hell).
Clear Mission 05 without V's demons getting stalemated (any difficulty except Heaven or Hell).
Clear the Bloody Palace with Nero.
Clear the Bloody Palace with Dante.
Clear the Bloody Palace with V.
Clear all missions as Vergil.
Acquire all of Vergil's skills.
Clear Mission 19 as Vergil without using any weapons other than Yamato. (Heaven or Hell excluded)
Clear the Bloody Palace as Vergil.