Full list of all 58 DmC: Devil May Cry achievements worth 1,250 gamerscore. It takes around 40-50 hours to unlock all of the achievements in the base game.
The base game contains 48 achievements worth 1,000 Gamerscore, and there is 1 DLC pack containing 10 achievements worth 250 Gamerscore.
Completed all missions on the Nephilim difficultly with a SSS rank
You have slayed 5,000 Demons
Completed all missions on Hell and Hell difficulty
Completed all missions on Heaven Or Hell difficulty
Completed all missions on the Dante Must Die difficulty
You have been awarded a 100% completion rank on all missions
You have found all of the Lost Souls
You have purchased all of Dante's combat upgrades
You completed Furnace of Souls without taking damage from the furnace
You navigated the Sky Bridge without hitting the lasers
You have Spent 50,000 Red Orbs
You have upgraded Dante's health to maximum
You have completed all of the Secret Missions
You have opened all 21 Secret Doors
You have found all 21 Keys
You reached the end of the descent on Mission 6 having killed all of the enemies
You killed 100 enemies using nothing but Angel weapons
You completed a level without taking any damage
Completed all missions on the Son of Sparda difficulty
You have upgraded Dante's Devil Trigger to maximum
You completed a level in 2 minutes or less
You killed 50 enemies using nothing but firearms
You have slayed 1,000 Demons
You earned 1,500 Style Bonuses
You have completed 10 of the Secret Missions
You defeated Vergil on any difficulty
You have defeated Mundus
You helped Vergil open the Vault
You killed 100 enemies using nothing but Demon weapons
You have spent 10,000 Red Orbs
You have acquired Kablooey
You have found half of the Lost Souls
You have defeated Mundus' spawn
Completed a mission with a SSS rank
You have acquired Revenant
You have acquired Aquila
You have acquired the Devil Trigger ability
You helped Phineas by retrieving his eye
You have acquired Eryx
You gained a SSS Style Rank during combat
You have defeated the Tyrant
You have acquired the Angel Boost ability
You have acquired Osiris
You have slayed 100 Demons
You have acquired Arbiter
You have defeated the Hunter
You purchased your first upgrade
You Killed 10 enemies by pushing them into the Hurricane ride
Completed all missions in Vergil's downfall on the Nephilim difficulty with a SSS rank
Completed Vergil's downfall on Hell and Hell difficulty
Completed Vergil's downfall on Heaven Or Hell difficulty
Completed Vergil's downfall on the Vergil Must Die difficulty
You've purchased all of Vergil's upgrades
You have been awarded a 100% completion rank on all missions in Vergil's downfall
Completed Vergil's downfall on the Son of Sparda difficulty
You've completed Vergil's downfall
You defeated an Imprisoner
You defeated a Wisp