Full list of all 84 Fallout 4 achievements worth 1,600 gamerscore. It takes around 80-100 hours to unlock all of the achievements in the base game on Xbox One.
The base game contains 50 achievements worth 1,000 Gamerscore, and there are 6 DLC packs containing 34 achievements worth 600 Gamerscore.
Complete "The Nuclear Option"
Complete "Ad Victoriam"
Complete "Blind Betrayal"
Complete "Nuclear Family"
Decide the Fate of the Commonwealth
Complete "Rockets' Red Glare"
Complete "Underground Undercover"
Complete "Powering Up"
Complete "Mankind-Redefined"
Complete "Institutionalized"
Complete "The Molecular Level"
Hack 50 Terminals
Complete "Hunter/Hunted"
Reach Maximum Happiness in a Large Settlement
Complete 50 Misc. Objectives
Reach Level 50
Reach Maximum Relationship Level with a Companion
Kill 5 Giant Creatures
Create 50 Weapon Mods
Craft 100 Items
Collect 20 Vault-Tec Bobbleheads
Join the Railroad
Complete 10 Side Quests
Join the Brotherhood of Steel
Complete "Dangerous Minds"
Complete "Reunions"
Complete "Unlikely Valentine"
Collect 10 Vault-Tec Bobbleheads
Get a Homerun
Kill 300 Creatures
Kill 300 People
Read 20 Magazines
Reach Level 25
Recruit 5 Separate Companions
Discover 100 Locations
Pick 50 Locks
Complete "Old Guns"
Complete "Taking Independence"
Ally with 3 Settlements
Placed A Grenade Or Mine While Pickpocketing
Reach Level 10
Build 100 Workshop Items
Get a Touchdown
Gather 1000 Resources Used For Crafting
Join the Minutemen
Complete "Sanctuary"
Reach Level 5
Complete "When Freedom Calls"
Enter The Wasteland
Play a Holotape Game
Complete "Restoring Order"
Build 10 Robot Mods
Complete "Headhunting"
Unlock 10 Robot Mods
Complete "Mechanical Menace"
Have 5 Tamed Creatures in a Settlement
Build One of Every Cage Type
Start a Spectated Arena Fight in a Settlement
Complete the quest "Close to Home"
Complete the quest "Cleansing the Land"
Complete the quest "The Way Life Should Be"
Defeat 30 Far Harbor Sea Creatures
Collect all issues of "The Islander's Almanac" magazine
Complete the quest "Where You Belong"
Discover 20 Far Harbor Locations
Unlock 3 Far Harbor Workshop Locations
Cook One of the New Far Harbor Recipes
Complete the quest "Far From Home"
Produce 100 objects from your builders
Display a weapon on a weapon rack, armor on an armor rack, and power armor in a power armor display.
Assign a settler to a pillory
Become Overseer
Equip Vault 88 suit and Pip-Boy on a settler
Unlock all Vault 88 build areas
Redeem 100,000 tickets at the Nuka-Cade
Complete "Power Play"
Create 20 different flavors of Nuka-Cola
Establish 8 Raider Camps in the Commonwealth
Complete "Home Sweet Home"
Defeat 40 Nuka-World Creatures while under the effect of any Nuka-Mix flavor
Complete "The Grand Tour"
Collect every issue of Scav! Magazine
Complete 12 quests for any Nuka-World Raider Gangs
Complete "Taken for a Ride"