Full list of all 84 Fallout 4 achievements worth 1,600 gamerscore. It takes around 80-100 hours to unlock all of the achievements in the base game on Xbox One.
The base game contains 50 achievements worth 1,000 Gamerscore, and there are 6 DLC packs containing 34 achievements worth 600 Gamerscore.
Reach Level 50
Complete "Nuclear Family"
Complete 50 Misc. Objectives
Reach Maximum Happiness in a Large Settlement
Create 50 Weapon Mods
Craft 100 Items
Kill 5 Giant Creatures
Placed A Grenade Or Mine While Pickpocketing
Complete "Rockets' Red Glare"
Hack 50 Terminals
Complete "Underground Undercover"
Complete "Powering Up"
Complete "The Nuclear Option"
Decide the Fate of the Commonwealth
Complete "Ad Victoriam"
Complete "Blind Betrayal"
Complete "Mankind-Redefined"
Recruit 5 Separate Companions
Complete "Institutionalized"
Complete "The Molecular Level"
Complete "Hunter/Hunted"
Reach Maximum Relationship Level with a Companion
Complete "Dangerous Minds"
Collect 20 Vault-Tec Bobbleheads
Pick 50 Locks
Collect 10 Vault-Tec Bobbleheads
Kill 300 People
Reach Level 25
Complete 10 Side Quests
Complete "Reunions"
Play a Holotape Game
Kill 300 Creatures
Complete "Old Guns"
Read 20 Magazines
Build 100 Workshop Items
Gather 1000 Resources Used For Crafting
Discover 100 Locations
Get a Homerun
Complete "Sanctuary"
Complete "Unlikely Valentine"
Join the Railroad
Complete "Taking Independence"
Ally with 3 Settlements
Reach Level 10
Join the Brotherhood of Steel
Join the Minutemen
Get a Touchdown
Reach Level 5
Complete "When Freedom Calls"
Enter The Wasteland
Complete "Restoring Order"
Complete "Headhunting"
Build 10 Robot Mods
Unlock 10 Robot Mods
Complete "Mechanical Menace"
Have 5 Tamed Creatures in a Settlement
Build One of Every Cage Type
Start a Spectated Arena Fight in a Settlement
Complete the quest "Close to Home"
Defeat 30 Far Harbor Sea Creatures
Complete the quest "Cleansing the Land"
Collect all issues of "The Islander's Almanac" magazine
Complete the quest "The Way Life Should Be"
Complete the quest "Where You Belong"
Cook One of the New Far Harbor Recipes
Unlock 3 Far Harbor Workshop Locations
Discover 20 Far Harbor Locations
Complete the quest "Far From Home"
Produce 100 objects from your builders
Display a weapon on a weapon rack, armor on an armor rack, and power armor in a power armor display.
Assign a settler to a pillory
Equip Vault 88 suit and Pip-Boy on a settler
Unlock all Vault 88 build areas
Become Overseer
Redeem 100,000 tickets at the Nuka-Cade
Complete "Power Play"
Defeat 40 Nuka-World Creatures while under the effect of any Nuka-Mix flavor
Create 20 different flavors of Nuka-Cola
Establish 8 Raider Camps in the Commonwealth
Complete "Home Sweet Home"
Complete 12 quests for any Nuka-World Raider Gangs
Collect every issue of Scav! Magazine
Complete "The Grand Tour"
Complete "Taken for a Ride"