Full list of all 84 Fallout 4 achievements worth 1,600 gamerscore. It takes around 80-100 hours to unlock all of the achievements in the base game on Xbox One.
The base game contains 50 achievements worth 1,000 Gamerscore, and there are 6 DLC packs containing 34 achievements worth 600 Gamerscore.
Reach Maximum Happiness in a Large Settlement
Complete "Ad Victoriam"
Complete "Blind Betrayal"
Complete "Nuclear Family"
Complete "The Nuclear Option"
Decide the Fate of the Commonwealth
Complete "Rockets' Red Glare"
Complete "Underground Undercover"
Complete "Powering Up"
Complete "Mankind-Redefined"
Complete "Institutionalized"
Complete "The Molecular Level"
Complete "Hunter/Hunted"
Complete 50 Misc. Objectives
Kill 5 Giant Creatures
Placed A Grenade Or Mine While Pickpocketing
Collect 20 Vault-Tec Bobbleheads
Create 50 Weapon Mods
Reach Level 50
Collect 10 Vault-Tec Bobbleheads
Join the Railroad
Build 100 Workshop Items
Complete 10 Side Quests
Complete "Old Guns"
Complete "Dangerous Minds"
Reach Maximum Relationship Level with a Companion
Hack 50 Terminals
Craft 100 Items
Complete "Reunions"
Recruit 5 Separate Companions
Get a Homerun
Kill 300 People
Complete "Taking Independence"
Reach Level 25
Complete "Unlikely Valentine"
Read 20 Magazines
Discover 100 Locations
Get a Touchdown
Kill 300 Creatures
Gather 1000 Resources Used For Crafting
Pick 50 Locks
Join the Brotherhood of Steel
Ally with 3 Settlements
Complete "Sanctuary"
Reach Level 10
Play a Holotape Game
Join the Minutemen
Reach Level 5
Complete "When Freedom Calls"
Enter The Wasteland
Complete "Restoring Order"
Unlock 10 Robot Mods
Complete "Headhunting"
Build 10 Robot Mods
Complete "Mechanical Menace"
Have 5 Tamed Creatures in a Settlement
Start a Spectated Arena Fight in a Settlement
Build One of Every Cage Type
Collect all issues of "The Islander's Almanac" magazine
Complete the quest "Close to Home"
Defeat 30 Far Harbor Sea Creatures
Complete the quest "Cleansing the Land"
Complete the quest "The Way Life Should Be"
Discover 20 Far Harbor Locations
Unlock 3 Far Harbor Workshop Locations
Cook One of the New Far Harbor Recipes
Complete the quest "Where You Belong"
Complete the quest "Far From Home"
Display a weapon on a weapon rack, armor on an armor rack, and power armor in a power armor display.
Assign a settler to a pillory
Produce 100 objects from your builders
Equip Vault 88 suit and Pip-Boy on a settler
Become Overseer
Unlock all Vault 88 build areas
Collect every issue of Scav! Magazine
Complete "The Grand Tour"
Complete "Taken for a Ride"
Complete 12 quests for any Nuka-World Raider Gangs
Create 20 different flavors of Nuka-Cola
Establish 8 Raider Camps in the Commonwealth
Defeat 40 Nuka-World Creatures while under the effect of any Nuka-Mix flavor
Redeem 100,000 tickets at the Nuka-Cade
Complete "Home Sweet Home"
Complete "Power Play"