Full list of all 84 Fallout 4 achievements worth 1,600 gamerscore. It takes around 80-100 hours to unlock all of the achievements in the base game on Xbox One.
The base game contains 50 achievements worth 1,000 Gamerscore, and there are 6 DLC packs containing 34 achievements worth 600 Gamerscore.
Reach Maximum Happiness in a Large Settlement
Complete "Nuclear Family"
Complete "Ad Victoriam"
Complete "Blind Betrayal"
Complete "The Nuclear Option"
Decide the Fate of the Commonwealth
Complete "Rockets' Red Glare"
Complete "Underground Undercover"
Complete "Powering Up"
Complete "Mankind-Redefined"
Collect 20 Vault-Tec Bobbleheads
Complete "Institutionalized"
Complete "The Molecular Level"
Complete "Hunter/Hunted"
Complete "Old Guns"
Placed A Grenade Or Mine While Pickpocketing
Complete 50 Misc. Objectives
Reach Level 50
Complete "Taking Independence"
Reach Maximum Relationship Level with a Companion
Hack 50 Terminals
Kill 5 Giant Creatures
Join the Brotherhood of Steel
Collect 10 Vault-Tec Bobbleheads
Join the Railroad
Complete "Dangerous Minds"
Complete "Reunions"
Join the Minutemen
Discover 100 Locations
Kill 300 People
Reach Level 25
Recruit 5 Separate Companions
Complete "Unlikely Valentine"
Complete 10 Side Quests
Ally with 3 Settlements
Craft 100 Items
Create 50 Weapon Mods
Read 20 Magazines
Complete "Sanctuary"
Kill 300 Creatures
Get a Touchdown
Build 100 Workshop Items
Get a Homerun
Pick 50 Locks
Gather 1000 Resources Used For Crafting
Reach Level 10
Reach Level 5
Complete "When Freedom Calls"
Enter The Wasteland
Play a Holotape Game
Complete "Restoring Order"
Complete "Headhunting"
Unlock 10 Robot Mods
Build 10 Robot Mods
Complete "Mechanical Menace"
Have 5 Tamed Creatures in a Settlement
Start a Spectated Arena Fight in a Settlement
Build One of Every Cage Type
Complete the quest "Close to Home"
Collect all issues of "The Islander's Almanac" magazine
Complete the quest "Cleansing the Land"
Complete the quest "The Way Life Should Be"
Defeat 30 Far Harbor Sea Creatures
Discover 20 Far Harbor Locations
Complete the quest "Where You Belong"
Unlock 3 Far Harbor Workshop Locations
Cook One of the New Far Harbor Recipes
Complete the quest "Far From Home"
Produce 100 objects from your builders
Display a weapon on a weapon rack, armor on an armor rack, and power armor in a power armor display.
Assign a settler to a pillory
Become Overseer
Equip Vault 88 suit and Pip-Boy on a settler
Unlock all Vault 88 build areas
Redeem 100,000 tickets at the Nuka-Cade
Create 20 different flavors of Nuka-Cola
Collect every issue of Scav! Magazine
Defeat 40 Nuka-World Creatures while under the effect of any Nuka-Mix flavor
Complete "Power Play"
Establish 8 Raider Camps in the Commonwealth
Complete "Home Sweet Home"
Complete 12 quests for any Nuka-World Raider Gangs
Complete "The Grand Tour"
Complete "Taken for a Ride"